Chen Xin Yu Wei, James Fiona M K
Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.
Can Vet J. 2025 Jan;66(1):64-69.
Limited reports exist on the antemortem presumptive diagnosis and treatment of feline neurocuterebriasis. A 3-day treatment protocol reported for 3 cats had no adverse effects. This protocol comprised ivermectin (0.4 mg/kg), diphenhydramine (4 mg/kg), and dexamethasone (0.1 mg/kg) given q24h.
To describe the treatment outcomes for cats that received the 3-day ivermectin protocol and antemortem diagnostic methods used before.
Medical records from a single veterinary referral centre were searched to identify cats treated with the 3-day protocol. Variables extracted included signalment, season, history, neurological examination findings, and advanced diagnostic tests, as well as outcomes based on follow-up.
Thirteen cats were diagnosed based on advanced imaging. Ten of 13 also underwent cerebrospinal fluid analysis. Other diagnostic factors included season (July through September), signalment (young to middle-aged), lifestyle (outdoor access), history (7/13 cats showed upper respiratory signs preceding neurological deficits), and clinical signs (central neurological deficits). After being treated with the 3-day ivermectin protocol, 10/13 cats improved. Three cats were euthanized after showing worsening clinical signs.
Outcomes using the 3-day ivermectin protocol appeared favorable. This provided insight about a treatment option for a periodic cause of feline encephalomyelopathy that has potential for deployment in first-opinion practice.
关于猫科动物神经皮肤蝇蛆病的生前推定诊断和治疗的报道有限。曾报道的针对3只猫的3天治疗方案未产生不良反应。该方案包括每24小时给予伊维菌素（0.4毫克/千克）、苯海拉明（4毫克/千克）和地塞米松（0.1毫克/千克）。
描述接受3天伊维菌素治疗方案的猫的治疗结果以及之前使用的生前诊断方法。
检索了一家单一兽医转诊中心的病历，以确定接受3天治疗方案治疗的猫。提取的变量包括特征、季节、病史、神经学检查结果、高级诊断测试以及基于随访的结果。
13只猫通过高级影像学检查被诊断。其中10只还进行了脑脊液分析。其他诊断因素包括季节（7月至9月）、特征（年轻至中年）、生活方式（有户外接触史）、病史（13只猫中有7只在出现神经功能缺损之前有上呼吸道症状）以及临床症状（中枢神经功能缺损）。在接受3天伊维菌素治疗方案后，13只猫中有10只病情改善。3只猫在临床症状恶化后实施了安乐死。
使用3天伊维菌素治疗方案的结果似乎良好。这为猫脑脊髓病的一种周期性病因提供了一种治疗选择的见解，该治疗方法有可能应用于初诊实践。
