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Serum B-cell maturation antigen could be a simple and accurate biomarker to identify and prognosticate monoclonal gammopathy of undetermined significance and smoldering multiple myeloma.

作者信息

Toho Masanori, Ikeda Daisuke, Aikawa Shuichi, Misono Chiho, Oura Mitsuaki, Fujii Fuminari, Sakuma Hajime, Uehara Atsushi, Tabata R Ikako, Narita Kentaro, Takeuchi Masami, Watari Tomohisa, Otsuka Yoshihito, Matsue Kosei

机构信息

Division of Hematology/Oncology, Department of Internal Medicine, Kameda Medical Center, Kamogawa.

Division of Hematology/Oncology, Department of Internal Medicine, Kameda Medical Center, Kamogawa, Japan; Department of Hematology/Oncology, Department of Medicine, Okayama University, Okayama.

出版信息

Haematologica. 2025 May 1;110(5):1207-1210. doi: 10.3324/haematol.2024.286842. Epub 2025 Jan 9.

DOI:10.3324/haematol.2024.286842
PMID:39781647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12050916/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb14/12050916/b2b0db42aa6f/1101207.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb14/12050916/3e305bee3928/1101207.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb14/12050916/b2b0db42aa6f/1101207.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb14/12050916/3e305bee3928/1101207.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb14/12050916/b2b0db42aa6f/1101207.fig2.jpg

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本文引用的文献

1
Soluble B-cell maturation antigen levels for disease monitoring in oligosecretory and nonsecretory relapsed multiple myeloma.寡分泌型和非分泌型复发多发性骨髓瘤中用于疾病监测的可溶性B细胞成熟抗原水平
Blood. 2025 Jan 30;145(5):526-532. doi: 10.1182/blood.2024026028.
2
Impact of soluble BCMA and non-T-cell factors on refractoriness to BCMA-targeting T-cell engagers in multiple myeloma.可溶性BCMA和非T细胞因子对多发性骨髓瘤中靶向BCMA的T细胞衔接器难治性的影响
Blood. 2024 Dec 19;144(25):2637-2651. doi: 10.1182/blood.2024026212.
3
Mode of progression in smoldering multiple myeloma: a study of 406 patients.
冒烟型多发性骨髓瘤的进展模式：一项对 406 例患者的研究。
Blood Cancer J. 2024 Jan 17;14(1):9. doi: 10.1038/s41408-024-00980-5.
4
Genetic defects of gamma-secretase genes in a multiple myeloma patient with high and dysregulated BCMA surface density: A case report.多发性骨髓瘤患者 BCMA 表面密度高且失调，存在γ-分泌酶基因突变：病例报告。
Br J Haematol. 2024 Feb;204(2):571-575. doi: 10.1111/bjh.19168. Epub 2023 Nov 13.
5
The exploration of B cell maturation antigen expression in plasma cell dyscrasias beyond multiple myeloma.探讨多发性骨髓瘤以外的浆细胞增生异常疾病中 B 细胞成熟抗原的表达。
BMC Cancer. 2023 Feb 7;23(1):123. doi: 10.1186/s12885-023-10591-1.
6
Serum BCMA levels predict outcomes in MGUS and smoldering myeloma patients.血清 BCMA 水平可预测 MGUS 和冒烟型骨髓瘤患者的结局。
Blood Cancer J. 2021 Jun 24;11(6):120. doi: 10.1038/s41408-021-00505-4.
7
Baseline serum B-cell maturation antigen levels predict time to disease progression for patients with smoldering multiple myeloma.基线血清 B 细胞成熟抗原水平可预测冒烟型多发性骨髓瘤患者的疾病进展时间。
Eur J Haematol. 2021 Sep;107(3):318-323. doi: 10.1111/ejh.13666. Epub 2021 Jun 14.
8
International Myeloma Working Group risk stratification model for smoldering multiple myeloma (SMM).国际骨髓瘤工作组冒烟型多发性骨髓瘤（SMM）的风险分层模型。
Blood Cancer J. 2020 Oct 16;10(10):102. doi: 10.1038/s41408-020-00366-3.
9
Estimating a normal reference range for serum B-cell maturation antigen levels for multiple myeloma patients.估算多发性骨髓瘤患者血清 B 细胞成熟抗原水平的正常参考范围。
Br J Haematol. 2021 Mar;192(6):1064-1067. doi: 10.1111/bjh.16673. Epub 2020 Apr 22.
10
Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria.纳入修订后 IMWG 诊断标准的冒烟型多发性骨髓瘤的风险分层。
Blood Cancer J. 2018 Jun 12;8(6):59. doi: 10.1038/s41408-018-0077-4.