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临床试验的重要性及其对当代医学的贡献:评论

Importance of clinical trials and contributions to contemporary medicine: commentary.

作者信息

Zhang Haofuzi, Jiang Xiaofan

机构信息

Department of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Institute of Neurosurgery of People's Liberation Army of China (PLA), PLA's Key Laboratory of Critical Care Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

出版信息

Ann Med. 2025 Dec;57(1):2451190. doi: 10.1080/07853890.2025.2451190. Epub 2025 Jan 9.

DOI:10.1080/07853890.2025.2451190
PMID:39781895
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11721763/
Abstract

Clinical trials are crucial to contemporary medicine, offering valuable insights into the safety, efficacy, and appropriate use of new treatments. They contribute to public health improvements, reduce healthcare costs, uncover new understandings of disease biology, and facilitate the development of therapies for rare conditions. Investing in clinical trials is therefore essential for advancing medical science and enhancing patient outcomes globally.

摘要

临床试验对当代医学至关重要,能为新疗法的安全性、有效性及合理使用提供宝贵见解。它们有助于改善公众健康、降低医疗成本、揭示对疾病生物学的新认识,并推动罕见病治疗方法的开发。因此,投资临床试验对于推动医学科学发展和在全球范围内改善患者治疗效果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8773/11721763/d1eb42fb9fde/IANN_A_2451190_UF0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8773/11721763/d1eb42fb9fde/IANN_A_2451190_UF0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8773/11721763/d1eb42fb9fde/IANN_A_2451190_UF0001_C.jpg

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Front Med (Lausanne). 2022 Oct 12;9:1037439. doi: 10.3389/fmed.2022.1037439. eCollection 2022.
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The challenges of clinical trials in rare diseases.罕见病临床试验的挑战。
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Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.未注册、中止和不发表随机试验:一项重复的荟萃分析研究。
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