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在清醒猴子的第一体感皮层局部注射蝇蕈醇所诱发的操纵行为缺陷。

Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey.

作者信息

Hikosaka O, Tanaka M, Sakamoto M, Iwamura Y

出版信息

Brain Res. 1985 Jan 28;325(1-2):375-80. doi: 10.1016/0006-8993(85)90344-0.

DOI:10.1016/0006-8993(85)90344-0
PMID:3978429
Abstract

Injection of muscimol (GABA agonist) in the finger region of area 2 of the alert monkey led to the striking yet reversible loss of finger coordination, thus disabling the monkey from picking up a small piece of food from a small hole or a funnel. Symptoms varied depending on sites of injection within the finger region. Neither weakness of hand or finger movements nor deficit in hand reach was observed.

摘要

在警觉猴子的2区手指区域注射蝇蕈醇(GABA激动剂)会导致手指协调性显著但可逆的丧失,从而使猴子无法从小孔或漏斗中捡起小块食物。症状因手指区域内的注射部位而异。未观察到手部或手指运动无力或伸手够物功能缺陷。

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