Smartphones can extend the reach of evidence-based gambling treatment services, yet the general acceptability of app-delivered gambling interventions remains unknown. This study examined the general acceptability and use of app-delivered gambling interventions, and predictors of both, among 173 Australian adults with a lifetime gambling problem (48.5% male, M = 46.4 years) recruited from an online panel. Overall, 55.5% of the sample had a positive attitude toward app-delivered gambling interventions, 8.1% had a neutral attitude, and 36.4% had a negative attitude. Furthermore, one in five participants (20.8%) reported using an app-delivered gambling intervention in their lifetime. Four dimensions of acceptability were examined, wherein 78.6% of participants endorsed confidence in the effectiveness of app-delivered gambling interventions and 66.5% perceived anonymity benefits, while 48.6% endorsed scepticism (e.g., potential to increase isolation) and 69.4% perceived technology-related threats (e.g., difficulty learning and applying app-based strategies). Positive predictors of acceptability and use included younger age, rural/regional residence, gambling expenditure, problem gambling severity, gambling harms, and use of professional support. Acceptability did not increase the likelihood of using app-delivered gambling interventions, however, which may suggest a translation gap. The findings support continued investment into the development and evaluation of app-delivered gambling interventions, with a focus on enhancing engagement and uptake. Uptake could be improved by promoting the effectiveness and anonymity of evidence-based app-delivered gambling interventions, particularly among receptive audiences (young people, rural/regional residents, those with greater problem gambling severity), while redressing scepticism and perceived technology-related threats among vulnerable subgroups (those with greater gambling expenditure and gambling-related harm).