Jain Aashita, Gupta D S, Donepudi Nandakishore, S Agrawal Saubhagya, Saini Deepika, Bijarniya Pooja
Teerthanker Mahaveer University, Morādābād, India.
Oral Maxillofac Surg. 2025 Jan 9;29(1):26. doi: 10.1007/s10006-025-01332-8.
It has been outlined that LTM (Lower third molar) extracted from patients in which grinding, cleaning, sterilization & demineralization prove to be highly effective as graft material for filling the alveolar socket of the very same patient. These investigations aim to assess the efficiency of ADDM (Autogenous Demineralized Dentin Matrix) graft in third molar extraction sockets.
To check the effectiveness of ADDM as graft material in extraction socket by evaluating pain, swelling, trismus, PD (Probing Depth) and bone density.
STUDY DESIGN, SETTING, SAMPLE: A prospective, randomized control trial was conducted at our institute. The patients were haphazardly, non-blindly alienated into two groups. Group A (45 patients) on the test side after LTM impaction surgery will receive ADDM graft material with bio-collagen membrane and Group B (45 patients) on the control side underwent LTM removal, with the alveolus left to heal conventionally by forming a blood clot.
Swelling showed significant difference between CG (Control Group) and TG (Test Group), the intergroup comparison of change in the swelling scores at seventh post-operative day (from pre-op level) was significantly higher in the TG (117.35) as compared to the CGs (115.92) (p = 0.001). A statistically significant difference in probing depth was also noted between the two groups, CG 4.46 ± 1.252 & TG 2.52 ± 0.641 in the post-operative examination at three months. In our study radiographical evaluation revealed progressive increase in bone density in TG (135.81 ± 8.73) when compared to CG (121.59 ± 13.83) over a period of three months. Pain and trismus evaluation did not reveal any significant difference between TG & CG.
The clinical results of the ADDM graft procedure demonstrate satisfactory outcomes in extraction sockets. The findings of this study highlight the importance of preservation methods in maintaining the periodontal pocket depth distal to the second molar and the remaining alveolar ridge following extraction.
已概述从患者体内提取的下颌第三磨牙(LTM),经研磨、清洁、消毒和脱矿处理后,作为填充同一患者牙槽窝的移植材料非常有效。这些研究旨在评估自体脱矿牙本质基质(ADDM)移植在下颌第三磨牙拔牙窝中的效果。
通过评估疼痛、肿胀、张口受限、探诊深度(PD)和骨密度,检查ADDM作为拔牙窝移植材料的有效性。
研究设计、设置、样本:在我们研究所进行了一项前瞻性随机对照试验。患者被随机、非盲地分为两组。A组(45例患者)在LTM阻生手术后,试验侧将接受ADDM移植材料和生物胶原膜,B组(45例患者)在对照侧进行LTM拔除,牙槽窝通过形成血凝块常规愈合。
肿胀在对照组(CG)和试验组(TG)之间显示出显著差异,术后第7天(相对于术前水平)肿胀评分变化的组间比较中,试验组(117.35)显著高于对照组(115.92)(p = 0.001)。两组之间在探诊深度上也存在统计学显著差异,术后3个月检查时,对照组为4.46±1.252,试验组为2.52±0.641。在我们的研究中,影像学评估显示,与对照组(121.59±13.83)相比,试验组(135.81±8.73)在3个月内骨密度逐渐增加。疼痛和张口受限评估未显示试验组和对照组之间有任何显著差异。
ADDM移植手术的临床结果表明在拔牙窝中取得了满意的效果。本研究结果强调了保存方法在维持拔牙后第二磨牙远中牙周袋深度和剩余牙槽嵴方面的重要性。