Frieders-Justin Viktor, Eckmann Christian, Glaser Benjamin
Section for Surgical Research, Medical University of Graz.
Department of Surgery, Klinik Donaustadt, Vienna Healthcare Group, Austria.
Curr Opin Infect Dis. 2025 Apr 1;38(2):136-142. doi: 10.1097/QCO.0000000000001088. Epub 2025 Jan 9.
To present standards and recent technical innovations in the surgical management of skin and soft tissue infections (SSTI).
SSTI are a frequent cause of presentation in the acute care setting. They can range from simple and uncomplicated to severe and necrotizing infections. Surgical management plays an important role in the treatment of uncomplicated SSTI. Recent evidence indicates that a subgroup of patients (e.g. immunocompromised patients) profits from a postoperative course of antibiotic treatment of 5-7 days. In diabetic foot infections (DFI), repeated debridement to remove necrotic tissue and control infection can prevent minor and major amputation. In necrotizing soft tissue infections (NSTI), early and aggressive surgical debridement is paramount. Recent advancements have explored skin-sparing techniques in selective cases.
The management of SSTIs requires a combination of surgical and antimicrobial strategies tailored to the type and severity of the infection. Further clinical research is necessary in order to define more accurately those collectives in severe SSTI who profit from a less aggressive surgical approach.
介绍皮肤和软组织感染(SSTI)外科治疗的标准及近期技术创新。
SSTI是急性护理环境中常见的就诊原因。其范围可从简单、非复杂性感染到严重、坏死性感染。外科治疗在非复杂性SSTI的治疗中发挥重要作用。近期证据表明,一部分患者(如免疫功能低下患者)术后接受5 - 7天抗生素治疗有益。在糖尿病足感染(DFI)中,反复清创以清除坏死组织并控制感染可预防大、小截肢。在坏死性软组织感染(NSTI)中,早期积极的外科清创至关重要。近期进展已在部分病例中探索了保留皮肤的技术。
SSTI的治疗需要根据感染类型和严重程度将手术和抗菌策略相结合。为了更准确地界定那些在严重SSTI中受益于较保守手术方法的人群,还需要进一步的临床研究。