Wu Xiaoyu, Wang Huaqin, Tan Ya, Tan Xiaoju, Zhao Xinge, Liu Xiaoling, Wang Wenli
The Clinical Nursing Teaching and Research Section of the Second Xiangya Hospital, 410011, Central South University, Changsha, Hunan Province, China.
The Clinical Nursing Teaching and Research Section of the Second Xiangya Hospital, 410011, Central South University, Changsha, Hunan Province, China.
Int J Orthop Trauma Nurs. 2025 Feb;56:101155. doi: 10.1016/j.ijotn.2024.101155. Epub 2024 Dec 27.
Deep venous thrombosis (DVT) of the lower extremity causes a major disease burden globally. Currently, oral anticoagulant therapy is used as the first-line treatment of DVT, however, medication non-adherence remains a serious problem for postoperative spinal surgery patients whose DVT incidence is at a high level.
To explore barriers and facilitators affecting patient oral anticoagulant medication adherence, based on guidance using the COM-B model.
This study was a qualitative study using a descriptive research design with in-depth and semi-structured interviews. Data were analyzed adopting traditional content analysis methods.
Based on the COM-B theoretical model, we identified 9 barriers and facilitators from capability, opportunity, and motivation domains.
Patients were confronted with barriers from capability, opportunity, and motivation domains, which were not isolated but interrelated. Future interventions should incorporate facilitators and barriers to address medication adherence issue with a holistic approach at multiple levels.
下肢深静脉血栓形成（DVT）在全球造成重大疾病负担。目前，口服抗凝治疗被用作DVT的一线治疗方法，然而，对于深静脉血栓发生率较高的脊柱手术术后患者，药物治疗依从性仍然是一个严重问题。
基于使用COM-B模型的指导，探讨影响患者口服抗凝药物治疗依从性的障碍和促进因素。
本研究是一项定性研究，采用描述性研究设计，进行深入的半结构化访谈。采用传统内容分析方法对数据进行分析。
基于COM-B理论模型，我们从能力、机会和动机领域识别出9个障碍和促进因素。
患者面临来自能力、机会和动机领域的障碍，这些障碍并非孤立存在，而是相互关联的。未来的干预措施应纳入促进因素和障碍，以多层次的整体方法解决药物治疗依从性问题。
