生物性别在大脑衰老过程中起着重要作用。
Biological sex matters in brain aging.
作者信息
Dubal Dena B, Murphy Coleen T, Suh Yousin, Benayoun Bérénice A
机构信息
Department of Neurology and Weill Institute for Neurosciences, University of California San Franciso, San Francisco, CA, USA; Bakar Aging Research Institute, University of California San Franciso, San Francisco, CA, USA.
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.
出版信息
Neuron. 2025 Jan 8;113(1):2-6. doi: 10.1016/j.neuron.2024.12.005.
Abstract
Every cell in the body has a biological sex. The expansion of aging research to investigate female- and male-specific biology heralds a major advance for human health. Unraveling and harnessing mechanistic etiologies of sex differences may reveal new diagnostics and therapeutics for the aging brain.
摘要
体内的每个细胞都有生物学性别。衰老研究的扩展以探究女性和男性特有的生物学特性，预示着人类健康领域的一项重大进展。揭示并利用性别差异的机制病因可能会为衰老大脑带来新的诊断方法和治疗手段。
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