菌株丰富度的蝴蝶效应影响着微生物群移植的疗效。
The butterfly effect of the strain richness influences the efficacy of microbiota transplantation.
作者信息
Wang Weihong, Pi Zheshun, Yu You, Zhang Faming
机构信息
Department of Microbiota Medicine & Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China; Jiangsu Engineering Research Center for Advanced Microbiota Medicine, Key Lab of Holistic Integrative Enterology, Nanjing Medical University, Nanjing, Jiangsu 210011, China.
Department of Microbiota Medicine & Medical Center for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210011, China; Jiangsu Engineering Research Center for Advanced Microbiota Medicine, Key Lab of Holistic Integrative Enterology, Nanjing Medical University, Nanjing, Jiangsu 210011, China.
出版信息
Cell Host Microbe. 2025 Jan 8;33(1):3-5. doi: 10.1016/j.chom.2024.12.010.
Strain-level variation in the gut microbiome modulates its impact on host health. Recently in Nature, Chen-Liaw et al. propose that strain richness is a crucial element in the gut ecosystem, thus influencing efficacy of fecal microbiota transplantation, and provide a theoretical foundation for optimizing microbiota-based treatments and developing microbiota medicine.
肠道微生物组的菌株水平变异调节其对宿主健康的影响。最近在《自然》杂志上，陈廖等人提出菌株丰富度是肠道生态系统中的一个关键要素，从而影响粪便微生物群移植的效果，并为优化基于微生物群的治疗方法和开发微生物群药物提供了理论基础。
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