犬非IgE过敏性抗体的诱导
Induction of non-IgE anaphylactic antibodies in dogs.
作者信息
Willemse A, Noordzij A, Rutten V P, Bernadina W E
出版信息
Clin Exp Immunol. 1985 Feb;59(2):351-8.
Abstract
Dogs immunized with o-DNCP-BSA or eggs of Toxocara canis developed anaphylactic antibodies other than IgE. The antibodies were heat-resistant at 56 degrees C for 2 hours, not reduced by 2-mercaptoethanol and PCA and P-K reactivity was only observed at 3-4 h sensitized sites of recipient skin. High titres of antigen-specific IgGd were determined by means of an ELISA technique.
摘要
用邻二硝基氯苯 - 牛血清白蛋白（o - DNCP - BSA）或犬弓首蛔虫卵免疫的狗产生了除IgE之外的过敏抗体。这些抗体在56℃下2小时耐热，不被2 - 巯基乙醇、PCA还原，并且仅在受体皮肤致敏部位3 - 4小时观察到被动皮肤过敏反应（PCA）和被动 - 即刻反应（P - K）反应。通过酶联免疫吸附测定（ELISA）技术测定了高滴度的抗原特异性IgGd。
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