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左右下肢急性症状性深静脉血栓形成的年龄、性别及诱发因素。

The age, sex, and provoked factors of acute symptomatic deep vein thrombosis on the left and right lower extremities.

作者信息

Ren Chong-Li, Sun Jian-Ming, Wang Hai-Yang, Fu Jian, Xu Ye-Liang, Wang Jin, Nie Meng-Lin

机构信息

Department of Abdominal Wall, Hernia, and Vascular Surgery, Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, China.

Department of Abdominal Wall, Hernia, and Vascular Surgery, Second Affiliated Hospital, Chongqing Medical University, Chongqing, 400010, China.

出版信息

Chin J Traumatol. 2025 Mar;28(2):96-100. doi: 10.1016/j.cjtee.2024.07.014. Epub 2024 Dec 27.

DOI:10.1016/j.cjtee.2024.07.014
PMID:39788835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11973693/
Abstract

PURPOSE

Deep vein thrombosis (DVT) of the left and right lower extremities was treated in the same way, but the left and right extremities received different levels of attention. This study aimed to investigate the differences between the right and left lower extremity deep vein thrombosis (LEDVT).

METHODS

Clinical characteristics of LEDVT patients from July 2020 to June 2022 were retrospectively analyzed to compare the incidence of LEDVT on different limbs, demographics, predisposing factors, and anatomical characteristics. The exclusion criteria were bilateral LEDVT and recurrent thrombosis. Measured data was analyzed using independent samples t-test or Mann-Whitney test. Count data were analyzed by Chi-square test. A p < 0.05 was considered a statistically significant difference.

RESULTS

There were 478 patients included in this study and the ratio of left to right LEDVT on the left and right limbs was 3.16:1 (363:115). Left LEDVT predominantly affected female, with the major aged > 50 years (50 - 60 years: 16.80%; > 60 years: 57.30%). The primary predisposing factor was iliac vein compression syndrome, with iliofemoral thrombosis being the main type. Male patients with LEDVT on the right limb were predominant and the age of onset was usually ≤ 60 years (52.17%). The main predisposing factor was recent surgery or trauma (< 30 days) and femoropopliteal thrombosis was the main type. In more detail, the left iliac vein was compressed mainly in the proximal segment, and the right iliac vein was compressed mainly in the intermediate and distal segments. Recent surgery or trauma to the locomotor system and genitourinary system often induced LEDVT.

CONCLUSION

The incidence of LEDVT on the left is significantly higher than that on the right. LEDVT on different sides has different characteristics, which is crucial for prevention and diagnosis in the relevant population so there are also differences in treatment of the affected limbs.

摘要

目的

左右下肢深静脉血栓形成(DVT)的治疗方式相同,但左右下肢受到的关注程度不同。本研究旨在探讨左右下肢深静脉血栓形成(LEDVT)之间的差异。

方法

回顾性分析2020年7月至2022年6月期间LEDVT患者的临床特征,以比较不同肢体LEDVT的发病率、人口统计学特征、诱发因素和解剖学特征。排除标准为双侧LEDVT和复发性血栓形成。计量资料采用独立样本t检验或Mann-Whitney检验进行分析。计数资料采用卡方检验进行分析。p<0.05被认为具有统计学显著差异。

结果

本研究共纳入478例患者,左右下肢LEDVT的比例为3.16:1(363:115)。左侧LEDVT主要影响女性,主要年龄>50岁(50 - 60岁:16.80%;>60岁:57.30%)。主要诱发因素为髂静脉压迫综合征,主要类型为髂股静脉血栓形成。右侧肢体LEDVT的男性患者居多,发病年龄通常≤60岁(52.17%)。主要诱发因素为近期手术或创伤(<30天),主要类型为股腘静脉血栓形成。更详细地说,左侧髂静脉主要在近端受压,右侧髂静脉主要在中远端受压。运动系统和泌尿生殖系统的近期手术或创伤常诱发LEDVT。

结论

左侧LEDVT的发病率显著高于右侧。不同侧的LEDVT具有不同的特征,这对于相关人群的预防和诊断至关重要,因此患肢的治疗也存在差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b39/11973693/ca51ec3dcd94/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b39/11973693/34c4900a5190/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b39/11973693/ca51ec3dcd94/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b39/11973693/34c4900a5190/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b39/11973693/ca51ec3dcd94/gr2.jpg

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本文引用的文献

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Dynamic Changes and Relevant Factors of Perioperative Deep Vein Thrombosis in Patients with Thoracolumbar Fractures Caused by High-Energy Injuries.高能损伤致胸腰椎骨折患者围手术期深静脉血栓的动态变化及相关因素。
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Left iliac vein involvement is a protective factor against symptomatic pulmonary embolism in lower left extremity deep vein thrombosis.
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J Vasc Surg Venous Lymphat Disord. 2022 Nov;10(6):1272-1278. doi: 10.1016/j.jvsv.2022.05.015. Epub 2022 Aug 2.
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