74738Shandong University of Traditional Chinese Medicine, Jinan, China.
Laizhou Hospital of Traditional Chinese Medicine, Laizhou, China.
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211002900. doi: 10.1177/10760296211002900.
The objective of this work is to discuss and analyze the related factors of lower extremity fracture complicated by preoperative deep vein thrombosis (DVT).
A total of 11,891 patients with closed fractures of lower extremities were selected. By analyzing each patient's gender, age, presence or absence of diabetes and hypertension, preoperative plasma D-dimer level, and color Doppler ultrasound of the lower extremity vein, the pertinent factors of the patients with lower extremity fractures complicated by preoperative DVT were analyzed.
A total of 578 with preoperative DVT were detected, displaying a total incidence of 4.86%. All patients were categorized into either the DVT group or non-DVT group. The results demonstrate that there were statistically significant differences between the 2 groups in age, the presence of diabetes and hypertension, the fracture site, and the preoperative plasma D-dimer level ( < 0.05). Logistic multivariate analysis revealed that age, the presence of diabetes, and the preoperative plasma D-dimer level of patients were independent risk factors for lower extremity fracture complicated by DVT.
Age, the presence of diabetes, the fracture site, and increased D-dimer levels were found to be potential risk factors and indicators for preoperative DVT in patients with lower extremity fractures. In addition, the preoperative plasma D-dimer level has certain guiding significance for the prediction of venous thrombosis after lower extremity fracture, which is conducive to the early prediction and diagnosis of DVT, but it often must be followed with good clinic acumen and examinations.
本研究旨在探讨和分析下肢骨折术前并发深静脉血栓（DVT）的相关因素。
选择 11891 例闭合性下肢骨折患者，通过分析每位患者的性别、年龄、是否合并糖尿病和高血压、术前血浆 D-二聚体水平以及下肢静脉彩色多普勒超声，分析下肢骨折术前并发 DVT 的相关因素。
共检出术前 DVT 患者 578 例，总发生率为 4.86%。所有患者分为 DVT 组和非 DVT 组。结果显示，两组患者在年龄、合并糖尿病和高血压、骨折部位和术前血浆 D-二聚体水平方面存在统计学差异（<0.05）。多因素 logistic 分析显示，年龄、糖尿病以及术前血浆 D-二聚体水平是下肢骨折合并 DVT 的独立危险因素。
年龄、糖尿病、骨折部位和 D-二聚体水平升高是下肢骨折患者术前 DVT 的潜在危险因素和指标。此外，术前血浆 D-二聚体水平对下肢骨折后静脉血栓形成具有一定的预测意义，有助于早期预测和诊断 DVT，但常常需要结合良好的临床敏锐度和检查。
