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用于协同对抗耐抗生素细菌的硫醇封端的卤胺配体与光热金纳米棒

Thiol-terminated -halamine ligands to photothermal gold nanorods for synergistically combating antibiotic-resistant bacteria.

作者信息

Gerile Saren, Wu Xiaojie, Kang Jing, Qi Yansong, Dong Alideertu

机构信息

College of Chemistry and Chemical Engineering, Inner Mongolia University, Engineering Research Center of Dairy Quality and Safety Control Technology, Ministry of Education, Inner Mongolia University, Hohhot 010021, P. R. China.

Orthopedic Center (Sports Medicine Center), Inner Mongolia People's Hospital, Hohhot 010017, People's Republic of China.

出版信息

Soft Matter. 2025 Jan 22;21(4):556-560. doi: 10.1039/d4sm01214c.

Abstract

Bio-friendly antibacterial -halamine polymers were used to modify gold nanorods (GNR@pAMPS-Cl), which showed excellent antimicrobial activity against antibiotic-resistant bacteria and accelerated the healing of MRSA-infected wounds. This work provides a new strategy for the preparation of nanoscale antibacterial materials.

摘要

生物友好型抗菌卤胺聚合物被用于修饰金纳米棒(GNR@pAMPS-Cl),其对耐药细菌表现出优异的抗菌活性,并加速了耐甲氧西林金黄色葡萄球菌感染伤口的愈合。这项工作为制备纳米级抗菌材料提供了一种新策略。

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