2024年8月至11月，日本发生的11型艾柯病毒感染所致新生儿急性肝衰竭病例。
Neonatal acute liver failure cases with echovirus 11 infections, Japan, August to November 2024.
作者信息
Ikuse Tatsuki, Matsui Toshihiro, Shoji Kensuke, Kono Naoko, Yamada Masaki, Ogimi Chikara, Takahashi Chika, Funaki Takanori, Ide Kentaro, Matsumoto Shotaro, Ito Reiko, Shimabukuro Rinshu, Gocho Yoshihiro, Hayakawa Itaru, Ishikawa Takashi, Sakamoto Seisuke, Kasahara Mureo, Igarashi Takashi
机构信息
Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan.
Infectious Disease Control Division, Setagaya Public Health Center, Tokyo, Japan.
出版信息
Euro Surveill. 2025 Jan;30(1). doi: 10.2807/1560-7917.ES.2025.30.1.2400822.
In 2022-23, several European countries reported paediatric acute liver failure (ALF) with enterovirus infection. In August-November 2024, three neonatal cases of ALF with echovirus 11 (E11) were reported in Tokyo, Japan. All neonates developed irreversible multiple-organ failure and died. The E11 strain belonged to the new lineage 1, which was the same as strains isolated from neonatal ALF cases in Europe in 2022-23.
2022年至2023年期间，几个欧洲国家报告了肠道病毒感染所致的小儿急性肝衰竭（ALF）。2024年8月至11月，日本东京报告了3例感染埃可病毒11型（E11）的新生儿急性肝衰竭病例。所有新生儿均出现不可逆的多器官功能衰竭并死亡。E11毒株属于新的1型谱系，与2022年至2023年在欧洲从新生儿急性肝衰竭病例中分离出的毒株相同。
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