Nakai Chikashi, Zhang Cheng, Kitahara Hiroto, Shults Christian, Waksman Ron, Molina Ezequiel J
Division of Cardiac Surgery, MedStar Washington Hospital Center, Washington DC.
Division of Cardiology, MedStar Washington Hospital Center, Washington DC.
Ann Thorac Surg Short Rep. 2023 Feb 21;1(2):298-301. doi: 10.1016/j.atssr.2023.02.005. eCollection 2023 Jun.
The purpose of this study was to evaluate postoperative outcomes with the use of bilateral internal mammary artery (BIMA) conduits in obese patients.
Between January 2003 and December 2018, 8109 patients underwent isolated coronary artery bypass grafting, including 7218 (89%) treated with single internal mammary artery (SIMA) and 891 (11%) treated with BIMA grafts. Patients were divided into 3 groups according to preoperative body mass index (BMI): normal, BMI <25 kg/m (22.2%); overweight, BMI of 25 to <30 kg/m (37.2%); and obese, BMI ≥30 kg/m (40.6%). In each group, BIMA and SIMA patients were compared to investigate 30-day mortality and postoperative complications. Significant baseline differences were observed between the 3 BMI groups, and such differences were adjusted by inverse probability weighting matching.
Thirty-day mortality, deep sternal wound infection (DSWI) rates, and length of hospital stay were 1.4%, 0.5%, and 6.0 ± 9.1 days for the normal group; 0.2%, 1.0%, and 5.5 ± 4.2 days for the overweight group; and 0.9%, 1.8%, and 5.5 ± 4.0 days for the obese group. There was no significant difference in 30-day mortality, incidence of DSWI, and hospital stay between BIMA and SIMA groups, except in the obese group, in which the rate of DSWI was significantly higher in the BIMA patients (3.4% vs 0%; = .02).
BIMA grafts in obese patients can be used without an increase of the 30-day mortality and hospital stay. However, the use of BIMA grafts in obese patients may lead to an increase of postoperative DSWI.
本研究的目的是评估肥胖患者使用双侧乳内动脉(BIMA)导管的术后结果。
2003年1月至2018年12月期间,8109例患者接受了单纯冠状动脉旁路移植术,其中7218例(89%)采用单支乳内动脉(SIMA)治疗,891例(11%)采用BIMA移植治疗。根据术前体重指数(BMI)将患者分为3组:正常组,BMI<25kg/m²(22.2%);超重组,BMI为25至<30kg/m²(37.2%);肥胖组,BMI≥30kg/m²(40.6%)。在每组中,比较BIMA和SIMA患者的30天死亡率和术后并发症。在3个BMI组之间观察到显著的基线差异,并通过逆概率加权匹配进行调整。
正常组的30天死亡率、深部胸骨伤口感染(DSWI)率和住院时间分别为1.4%、0.5%和6.0±9.1天;超重组分别为0.2%、1.0%和5.5±4.2天;肥胖组分别为0.9%、1.8%和5.5±4.0天。BIMA组和SIMA组之间的30天死亡率、DSWI发生率和住院时间没有显著差异,但肥胖组除外,其中BIMA患者的DSWI发生率显著更高(3.4%对0%;P=.02)。
肥胖患者使用BIMA移植不会增加30天死亡率和住院时间。然而,肥胖患者使用BIMA移植可能会导致术后DSWI增加。