大鼠会阴提肛肌的蛋白质表型与基因表达

Protein phenotype and gene expression in the rat perineal levator ani muscle.

作者信息

Gagnon J, Tremblay R R, Rogers P A

出版信息

Comp Biochem Physiol B. 1985;80(2):279-86. doi: 10.1016/0305-0491(85)90208-1.

Abstract

The rat perineal levator ani (LA) and bulbocavernosus (BC) muscles are homogeneously type 2B fibers as determined by Ca, Mg-ATPase activity. The LA and extensor digitorum longus (EDL) muscles contain similar quantities of creatine kinase and several glycolytic enzymes despite significant differences in fiber composition. The LA muscles synthesizes and accumulates only the fast isoforms of protein C, myosin heavy chain and myosin light chains.

摘要

通过钙、镁 - ATP酶活性测定，大鼠会阴提肛肌（LA）和球海绵体肌（BC）均为均匀的2B型纤维。尽管纤维组成存在显著差异，但提肛肌和趾长伸肌（EDL）所含的肌酸激酶和几种糖酵解酶的量相似。提肛肌仅合成并积累蛋白C、肌球蛋白重链和肌球蛋白轻链的快速同工型。