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晚期表现为隆突下巨大肿块的胸腺腺癌。

Thymic Adenocarcinoma Presenting Late as a Large Subcarinal Mass.

作者信息

Lee Sangjun, Na Kwon Joong, Park Samina, Lim Sojung, Jeon Yoon Kyung, Lee Hyun Joo, Park In Kyu, Kang Chang Hyun, Kim Young Tae

机构信息

Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.

Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.

出版信息

Ann Thorac Surg Short Rep. 2023 Mar 4;1(2):266-269. doi: 10.1016/j.atssr.2023.02.017. eCollection 2023 Jun.

DOI:10.1016/j.atssr.2023.02.017
PMID:39790334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708290/
Abstract

Thymic malignant neoplasms mostly occur in the anterior mediastinum. Less than 5% occur in the middle or posterior mediastinum. This report describes a large subcarinal mass incidentally discovered during follow-up magnetic resonance imaging for prostate cancer operation. After multidisciplinary discussion, chemotherapy was deemed ineffective, and complete tumor resection through right posterolateral thoracotomy was performed. The operation was uneventful, and the patient recovered smoothly. Immunohistochemistry and pathologic examination revealed thymic adenocarcinoma. Although very rare, thymic adenocarcinomas should be considered in the differential diagnosis of middle mediastinal masses.

摘要

胸腺恶性肿瘤大多发生在前纵隔。不到5%发生在中纵隔或后纵隔。本报告描述了一例在前列腺癌手术后的随访磁共振成像中偶然发现的隆突下大肿块。经过多学科讨论,认为化疗无效,遂通过右后外侧开胸进行了肿瘤完整切除。手术过程顺利,患者恢复良好。免疫组织化学和病理检查显示为胸腺腺癌。尽管非常罕见,但在中纵隔肿块的鉴别诊断中应考虑胸腺腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/11708290/6083ceb5e109/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/11708290/9629f11f8488/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/11708290/6083ceb5e109/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/11708290/9629f11f8488/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5f/11708290/6083ceb5e109/gr2.jpg

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本文引用的文献

1
Primary thymic adenocarcinomas: a clinicopathological and immunohistochemical study of 16 cases with emphasis on the morphological spectrum of differentiation.原发性胸腺腺癌:16 例临床病理和免疫组化研究,重点关注分化的形态谱。
Hum Pathol. 2018 Apr;74:73-82. doi: 10.1016/j.humpath.2018.01.011. Epub 2018 Jan 12.
2
Thymic carcinoma outcomes and prognosis: results of an international analysis.胸腺癌的结局和预后:国际分析结果。
J Thorac Cardiovasc Surg. 2015 Jan;149(1):95-100, 101.e1-2. doi: 10.1016/j.jtcvs.2014.09.124. Epub 2014 Oct 5.
3
Primary adenocarcinoma of the thymus: an immunohistochemical and molecular study with review of the literature.
胸腺原发性腺癌:一项免疫组织化学和分子研究并文献复习
BMC Clin Pathol. 2013 May 31;13(1):17. doi: 10.1186/1472-6890-13-17.
4
Uncommon primary mediastinal tumours.罕见的原发性纵隔肿瘤。
Lancet Oncol. 2004 Feb;5(2):107-18. doi: 10.1016/S1470-2045(04)01385-3.
5
Adenocarcinoma of the thymus: report of two cases, including a previously undescribed mucinous subtype.胸腺腺癌:两例报告,包括一种此前未描述过的黏液性亚型。
Am J Surg Pathol. 2003 Jan;27(1):124-30. doi: 10.1097/00000478-200301000-00014.