Degreef H, Dooms-Goossens A
Contact Dermatitis. 1985 Jan;12(1):33-7. doi: 10.1111/j.1600-0536.1985.tb01036.x.
23 patients who had used silver sulfadiazine cream were patch tested. No reactions to the active principle occurred but 2 vehicle components, cetyl alcohol and propylene glycol, were positive. No sulfonamide-sensitive subject reacted to silver sulfadiazine. There is no evidence that silver sulfadiazine has a contact sensitizing potential or that it is contra-indicated for patients with a history of sulfonamide hypersensitivity.
对23名使用过磺胺嘧啶银乳膏的患者进行了斑贴试验。未出现对活性成分的反应,但有2种赋形剂成分,即鲸蜡醇和丙二醇,呈阳性反应。对磺胺类药物敏感的患者对磺胺嘧啶银均无反应。没有证据表明磺胺嘧啶银具有接触致敏的可能性,也没有证据表明它对有磺胺类药物过敏史的患者禁用。