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Propylene glycol as a cause of an elevated serum osmolality.

作者信息

Bekeris L, Baker C, Fenton J, Kimball D, Bermes E

出版信息

Am J Clin Pathol. 1979 Oct;72(4):633-6. doi: 10.1093/ajcp/72.4.633.

DOI:10.1093/ajcp/72.4.633
PMID:495568
Abstract

Two severely burned patients experienced the onset of marked hyperosmolality during topical treatment with a cream containing silver sulfadiazine as an antimicrobial agent. Serum samples from both patients were studied for the presence of substances absorbed from the vehicle of the cream. Prophylene glycol, in concentrations which were high enough to account for the difference between calculated and measured osmolality, was demonstrated in the sera of these patients by gas chromatography.

摘要

相似文献

1
Propylene glycol as a cause of an elevated serum osmolality.
Am J Clin Pathol. 1979 Oct;72(4):633-6. doi: 10.1093/ajcp/72.4.633.
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Hyperosmolality induced by propylene glycol. A complication of silver sulfadiazine therapy.
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Hyperosmolality related to propylene glycol in an infant treated with enoximone infusion.在接受依诺昔酮输注治疗的婴儿中与丙二醇相关的高渗性。
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Control of experimental burn wound infections: comparative delivery of the antimicrobial agent (silver sulfadiazine) either from a cream base or from a solid synthetic dressing.实验性烧伤创面感染的控制：抗菌剂（磺胺嘧啶银）从乳膏基质或固体合成敷料中的比较性给药。
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