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胸锁关节的轴外脊索瘤

Extra-axial Chordoma of the Sternoclavicular Joint.

作者信息

Palleiko Benjamin A, Lim Chelsea Jeewoo, Dickson Kevin M, Bludevich Bryce M, Bai Shi, Akalin Ali, Maxfield Mark W, Uy Karl, Lou Feiran

机构信息

Division of Thoracic Surgery, Department of Surgery, UMass Chan Medical School, Worcester, Massachusetts.

Department of Pathology, UMass Chan Medical School, Worcester, Massachusetts.

出版信息

Ann Thorac Surg Short Rep. 2022 Oct 13;1(1):131-133. doi: 10.1016/j.atssr.2022.10.004. eCollection 2023 Mar.

DOI:10.1016/j.atssr.2022.10.004
PMID:39790525
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708656/
Abstract

Chordomas are rare, slowly growing, aggressive primary bone tumors that originate from notochord remnants and occur almost exclusively in the axial skeleton. Here, we describe a patient with an enlarging right-sided neck mass that was later diagnosed as a sternoclavicular joint chondroid chordoma. En bloc surgical resection was accomplished with negative margins. The patient continues to do well 15 months after resection without radiotherapy. This case highlights the importance of considering a wide differential in managing sternoclavicular joint tumors.

摘要

脊索瘤是一种罕见的、生长缓慢但具有侵袭性的原发性骨肿瘤,起源于脊索残余组织,几乎仅发生于中轴骨骼。在此,我们描述一名患者,其右侧颈部肿物逐渐增大,后来被诊断为胸锁关节软骨样脊索瘤。手术整块切除,切缘阴性。患者术后15个月情况良好,未接受放疗。该病例强调了在处理胸锁关节肿瘤时考虑广泛鉴别诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4a/11708656/29714200e7a8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4a/11708656/d535c32e8a35/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4a/11708656/29714200e7a8/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4a/11708656/d535c32e8a35/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e4a/11708656/29714200e7a8/gr2.jpg

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本文引用的文献

1
Imaging features of cartilaginous tumors of the head and neck.头颈部软骨肿瘤的影像学特征。
J Clin Imaging Sci. 2021 Dec 4;11:66. doi: 10.25259/JCIS_186_2021. eCollection 2021.
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Intra-articular extra-axial chordoma of the wrist: a case report with review of the current literature.腕关节关节内椎管外脊索瘤:一例病例报告并文献复习。
Skeletal Radiol. 2019 Dec;48(12):2015-2020. doi: 10.1007/s00256-019-03228-7. Epub 2019 May 18.
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Current treatment strategy for newly diagnosed chordoma of the mobile spine and sacrum: results of an international survey.
活动脊柱和骶骨新诊断脊索瘤的当前治疗策略:一项国际调查结果
J Neurosurg Spine. 2018 Oct 19;30(1):119-125. doi: 10.3171/2018.6.SPINE18362. Print 2019 Jan 1.
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Extra-axial chordomas.轴外脊索瘤
Ann R Coll Surg Engl. 2016 May;98(5):324-8. doi: 10.1308/rcsann.2016.0138.
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Chordomas: A Review.脊索瘤:综述
Neurosurg Clin N Am. 2015 Jul;26(3):437-52. doi: 10.1016/j.nec.2015.03.012.
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Chordoma: the entity.脊索瘤:实体
Biochim Biophys Acta. 2014 Dec;1846(2):655-69. doi: 10.1016/j.bbcan.2014.07.012. Epub 2014 Sep 3.
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Surgical management of primary bone tumors of the spine: validation of an approach to enhance cure and reduce local recurrence.脊柱原发性骨肿瘤的外科治疗:一种增强治愈率和降低局部复发率方法的验证。
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Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas.Brachyury是脊索发育的关键调节因子,是脊索瘤的一种新型生物标志物。
J Pathol. 2006 Jun;209(2):157-65. doi: 10.1002/path.1969.