Allen Marah Aymen, Ansari Danya, Naveed Sadiq
Ms. Allen is a medical student, University of New England College of Osteopathic Medicine in Portland, Maine.
Dr. Ansari is with Islamabad Medical and Dental College in Islamabad, Pakistan. Dr. Naveed is Psychiatry Program Director, Eastern Connecticut Health Network in Manchester, Connecticut.
Innov Clin Neurosci. 2024 Dec 1;21(10):22-24. eCollection 2024 Oct-Dec.
Fluoxetine, a selective serotonin reuptake inhibitor (SSRI), is one of the most widely prescribed antidepressant drugs in the United States due to its safety and efficacy. SSRIs are the first-line treatment for major depressive disorder and are also indicated for anxiety disorders, eating disorders, bipolar disorder, post-traumatic stress disorder, and obsessive-compulsive disorder. Common side effects of SSRIs include insomnia, nausea, anxiety, headache, weight change, sexual dysfunction, and suicide risk. Seizures are a less common side effect of fluoxetine. This article presents the case of 19-year-old transgender male patient who developed seizures as a side effect of an intentional overdose of fluoxetine. Although marketed frequently as a safe medication, providers should be aware of the adverse effects of fluoxetine.
氟西汀是一种选择性5-羟色胺再摄取抑制剂（SSRI），因其安全性和有效性，它是美国处方量最广泛的抗抑郁药物之一。SSRI是重度抑郁症的一线治疗药物，也适用于焦虑症、饮食失调症、双相情感障碍、创伤后应激障碍和强迫症。SSRI的常见副作用包括失眠、恶心、焦虑、头痛、体重变化、性功能障碍和自杀风险。癫痫发作是氟西汀较不常见的副作用。本文介绍了一名19岁的跨性别男性患者的病例，该患者因故意过量服用氟西汀而出现癫痫发作的副作用。尽管氟西汀常被宣传为一种安全的药物，但医疗服务提供者应了解其不良反应。
