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原发性脾脏弥漫性大B细胞淋巴瘤伴胃脾瘘:病例报告

Primary splenic diffuse large B-cell lymphoma presenting with a gastrosplenic fistula: Case report.

作者信息

Nawaz Hurerah, Greaser Josh, Kazi Irfan Amir, Nasrullah Ayesha

机构信息

RCSI - Medical University of Bahrain, Busaiteen, Bahrain.

University of Missouri, Columbia, MO, USA.

出版信息

Radiol Case Rep. 2024 Dec 15;20(3):1359-1362. doi: 10.1016/j.radcr.2024.11.072. eCollection 2025 Mar.

DOI:10.1016/j.radcr.2024.11.072
PMID:39791123
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11714051/
Abstract

Primary splenic diffuse large B-cell lymphoma (PS-DLBCL) is a rare manifestation of malignant lymphoma. Although DLBCL is the most common subtype of non-Hodgkin lymphoma, primary splenic involvement is uncommon. Additionally, a gastrosplenic fistula at initial presentation is even more rare and poses a diagnostic challenge for the radiologist. The clinical and imaging picture can be identical to a splenic abscess with a secondary gastrosplenic fistula formation (GSF), leading to a diagnostic conundrum. Hence, radiologists need to be familiar with this entity for correct diagnosis and appropriate clinical management.

摘要

原发性脾脏弥漫性大B细胞淋巴瘤(PS-DLBCL)是恶性淋巴瘤的一种罕见表现形式。虽然弥漫性大B细胞淋巴瘤是非霍奇金淋巴瘤最常见的亚型,但原发性脾脏受累并不常见。此外,初诊时出现胃脾瘘更为罕见,给放射科医生带来了诊断挑战。其临床和影像学表现可能与伴有继发性胃脾瘘形成(GSF)的脾脓肿相同,导致诊断难题。因此,放射科医生需要熟悉这一实体,以便做出正确诊断和进行适当的临床管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/f8a2ab467a62/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/0566f570e97a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/f8a2ab467a62/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/0566f570e97a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/f8a2ab467a62/gr2.jpg

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本文引用的文献

1
Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature.胃脾瘘由于脾淋巴瘤:两例病例报告并文献复习。
J Med Case Rep. 2024 Mar 7;18(1):136. doi: 10.1186/s13256-024-04441-2.
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Splenic abscess with spontaneous gastrosplenic fistula: case report and review of the literature.脾脓肿合并自发性胃脾瘘:病例报告及文献复习
J Surg Case Rep. 2023 Dec 5;2023(12):rjad647. doi: 10.1093/jscr/rjad647. eCollection 2023 Dec.
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Primary splenic diffuse large B-cell lymphoma presenting as a splenic abscess.
以脾脓肿形式呈现的原发性脾脏弥漫性大B细胞淋巴瘤。
EJHaem. 2023 Jan 24;4(1):226-231. doi: 10.1002/jha2.642. eCollection 2023 Feb.
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DLBCL 1L-What to Expect beyond R-CHOP?弥漫性大B细胞淋巴瘤1线治疗——R-CHOP方案之外还有什么可期待的?
Cancers (Basel). 2022 Mar 11;14(6):1453. doi: 10.3390/cancers14061453.
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Algorithmic Approach to the Splenic Lesion Based on Radiologic-Pathologic Correlation.基于放射学-病理学相关性的脾脏病变算法研究方法
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Characteristics of primary splenic diffuse large B-cell lymphoma and role of splenectomy in improving survival.原发性脾脏弥漫性大 B 细胞淋巴瘤的特征及脾切除术对改善生存的作用。
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J Res Med Sci. 2012 Aug;17(8):805-7.