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原发性脾脏弥漫性大B细胞淋巴瘤伴胃脾瘘:病例报告

Primary splenic diffuse large B-cell lymphoma presenting with a gastrosplenic fistula: Case report.

作者信息

Nawaz Hurerah, Greaser Josh, Kazi Irfan Amir, Nasrullah Ayesha

机构信息

RCSI - Medical University of Bahrain, Busaiteen, Bahrain.

University of Missouri, Columbia, MO, USA.

出版信息

Radiol Case Rep. 2024 Dec 15;20(3):1359-1362. doi: 10.1016/j.radcr.2024.11.072. eCollection 2025 Mar.

Abstract

Primary splenic diffuse large B-cell lymphoma (PS-DLBCL) is a rare manifestation of malignant lymphoma. Although DLBCL is the most common subtype of non-Hodgkin lymphoma, primary splenic involvement is uncommon. Additionally, a gastrosplenic fistula at initial presentation is even more rare and poses a diagnostic challenge for the radiologist. The clinical and imaging picture can be identical to a splenic abscess with a secondary gastrosplenic fistula formation (GSF), leading to a diagnostic conundrum. Hence, radiologists need to be familiar with this entity for correct diagnosis and appropriate clinical management.

摘要

原发性脾脏弥漫性大B细胞淋巴瘤(PS-DLBCL)是恶性淋巴瘤的一种罕见表现形式。虽然弥漫性大B细胞淋巴瘤是非霍奇金淋巴瘤最常见的亚型,但原发性脾脏受累并不常见。此外,初诊时出现胃脾瘘更为罕见,给放射科医生带来了诊断挑战。其临床和影像学表现可能与伴有继发性胃脾瘘形成(GSF)的脾脓肿相同,导致诊断难题。因此,放射科医生需要熟悉这一实体,以便做出正确诊断和进行适当的临床管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ee4/11714051/0566f570e97a/gr1.jpg

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