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胃出血的罕见鉴别诊断:胃脾瘘一例

An Unusual Differential Diagnosis of Gastric Haemorrhage: A Rare Case of Gastrosplenic Fistula.

作者信息

Cicchini Claudia, Santarelli Simona, Pugliese Francesco Rocco

机构信息

Department of Emergency Medicine, Sandro Pertini Hospital, Rome, Italy.

出版信息

Eur J Case Rep Intern Med. 2022 Aug 23;9(8):003419. doi: 10.12890/2022_003419. eCollection 2022.

Abstract

UNLABELLED

A gastrosplenic fistula is a rare complication of primary splenic lymphoma and a rare cause of massive upper gastrointestinal haemorrhage. We report a case of a spontaneous gastrosplenic fistula secondary to splenic large B-cell lymphoma. The patient was admitted to the emergency department with haematemesis. Oesophagogastroduodenoscopy showed a deep gastric ulcer, and a subsequent CT scan revealed a gastrosplenic fistula. Gastric biopsy demonstrated gastric mucosa with infiltration by large lymphoid cells. A multidisciplinary discussion on the management of this case was conducted. Primary surgical treatment of the fistula was not deemed indicated because the bleeding had stopped. The patient was stabilized, transfused, and then transferred to the oncology unit for chemotherapy. During hospitalization, lung metastases were found but the progressive worsening of the patient's general condition contraindicated chemotherapy. She was transferred to a hospice and died 2 months later of neoplastic cachexia. Gastrosplenic fistula is a rare condition. Prompt recognition of the underlying pathology can save the patient's life. We aim to highlight this rare complication of splenic lymphoma, discuss the presenting signs and symptoms, and explore the management options.

LEARNING POINTS

A gastrosplenic fistula is a rare complication of primary splenic lymphoma.It can cause massive upper gastrointestinal haemorrhage.Our patient was managed without surgery but died 2 months later from neoplastic cachexia.

摘要

未标注

胃脾瘘是原发性脾淋巴瘤的一种罕见并发症,也是大量上消化道出血的罕见原因。我们报告一例继发于脾大B细胞淋巴瘤的自发性胃脾瘘病例。患者因呕血入住急诊科。食管胃十二指肠镜检查显示有一个深部胃溃疡,随后的CT扫描显示存在胃脾瘘。胃活检显示胃黏膜有大淋巴细胞浸润。针对该病例的处理进行了多学科讨论。由于出血已停止,未考虑对瘘进行一期手术治疗。患者病情稳定后接受输血,然后转至肿瘤科进行化疗。住院期间发现有肺转移,但患者全身状况逐渐恶化,不适合进行化疗。她被转至临终关怀病房,2个月后因肿瘤性恶病质死亡。胃脾瘘是一种罕见疾病。及时识别潜在病理情况可挽救患者生命。我们旨在强调脾淋巴瘤的这种罕见并发症,讨论其临床表现和症状,并探讨处理方案。

学习要点

胃脾瘘是原发性脾淋巴瘤的一种罕见并发症。它可导致大量上消化道出血。我们的患者未接受手术治疗,2个月后死于肿瘤性恶病质。

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