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由位于15号染色体上的一个基因(MIC12)编码的人类肌肉细胞表面分化抗原。

Cell surface differentiation antigen of human muscle encoded by a gene (MIC12) on chromosome 15.

作者信息

Walsh F S, Quinn C A, Pym B, Goodfellow P N

出版信息

Cytogenet Cell Genet. 1985;39(1):51-6. doi: 10.1159/000132102.

DOI:10.1159/000132102
PMID:3979119
Abstract

Monoclonal antibody 30.2A8 was produced by a hybridoma made by fusing cells from rats that had been immunized with rat-human muscle cell hybrids. The 30.2A8 reacts with a differentiation antigen in human skeletal muscle that is synthesized by myoblasts but not myotubes. The gene controlling synthesis of the antigen recognized by 30.2A8 was found to be encoded by human chromosome 15.

摘要

单克隆抗体30.2A8由一种杂交瘤产生,该杂交瘤是通过将用大鼠-人肌肉细胞杂种免疫的大鼠细胞进行融合而制成的。30.2A8与人类骨骼肌中的一种分化抗原发生反应,该抗原由成肌细胞而非肌管合成。发现控制30.2A8所识别抗原合成的基因由人类15号染色体编码。

相似文献

1
Cell surface differentiation antigen of human muscle encoded by a gene (MIC12) on chromosome 15.由位于15号染色体上的一个基因(MIC12)编码的人类肌肉细胞表面分化抗原。
Cytogenet Cell Genet. 1985;39(1):51-6. doi: 10.1159/000132102.
2
Human muscle cell surface antigen 16.3A5 is encoded by a gene on chromosome 11.
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Human--rat muscle somatic cell hybrids form myotubes and express human muscle gene products.人-大鼠肌肉体细胞杂种形成肌管并表达人类肌肉基因产物。
Proc Natl Acad Sci U S A. 1981 Aug;78(8):5031-5. doi: 10.1073/pnas.78.8.5031.
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Surface antigen differentiation during human myogenesis in culture.培养过程中人类肌肉生成期间的表面抗原分化
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Identification of a cell-surface antigen produced by a gene on human chromosome 3 (cen-q22) and not expressed by Rhnull cells.鉴定一种由人类3号染色体(cen-q22)上的一个基因产生且Rhnull细胞不表达的细胞表面抗原。
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Expression and cellular localization of glucose transporters (GLUT1, GLUT3, GLUT4) during differentiation of myogenic cells isolated from rat foetuses.从大鼠胎儿分离的成肌细胞分化过程中葡萄糖转运蛋白(GLUT1、GLUT3、GLUT4)的表达及细胞定位
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引用本文的文献

1
Ultrastructural assessment of developmentally regulated cell surface antigens in human muscle cultures by immunogold labelling.通过免疫金标记对人肌肉培养物中发育调控的细胞表面抗原进行超微结构评估。
Histochem J. 1987 Mar;19(3):179-83. doi: 10.1007/BF01695142.