Rolston K V, Jones P G, Fainstein V, Bodey G P
Chest. 1985 Apr;87(4):503-6. doi: 10.1378/chest.87.4.503.
Five patients with microbiologically documented pulmonary infection caused by rapidly growing mycobacteria (Mycobacterium fortuitum and M chelonei) in patients with malignant diseases are described. These cases occurred over a seven-year period (1976 to 1983) and were found in patients with solid tumors and hematologic malignancies. Colonization (40 patients) with these organisms was far more frequent than true infection (five patients). Factors predisposing to infection were (1) antineoplastic chemotherapy and (2) previous pulmonary involvement with malignant disease. Mortality in these patients was due primarily to the underlying tumor. Although pulmonary infection caused by rapidly growing mycobacteria in patients with cancer is relatively uncommon, it might become an important diagnostic consideration in the presence of pulmonary infiltrates, especially in patients treated with intensive chemotherapeutic regimens.
本文描述了5例恶性疾病患者发生由快速生长分枝杆菌（偶然分枝杆菌和龟分枝杆菌）引起的经微生物学证实的肺部感染病例。这些病例发生在7年期间（1976年至1983年），见于实体瘤和血液系统恶性肿瘤患者。这些微生物的定植（40例患者）远比真正的感染（5例患者）常见。易导致感染的因素为：（1）抗肿瘤化疗；（2）既往肺部有恶性疾病累及。这些患者的死亡主要归因于基础肿瘤。虽然癌症患者中由快速生长分枝杆菌引起的肺部感染相对少见，但在出现肺部浸润时，尤其是接受强化化疗方案治疗的患者中，可能成为一个重要的诊断考虑因素。
