印度尼西亚城市社区膝关节骨关节炎的患病率、危险因素及生活质量：一项社区导向的基层医疗研究（COPCORD研究）

Prevalence, Risk Factors, and Quality of Life of Knee Osteoarthritis in Urban Community in Indonesia: A COPCORD Study.

作者信息

Kurniari Pande Ketut, Hidayat Rudy, Parlindungan Faisal, Pratama Mirza Zaka, Wibowo Suryo Anggoro Kusumo, Sarmidi Sumariyono, Wahono Cesarius Singgih, Suryana Bagus Putu Putra, Rahman Aditya Perdana, Partan Radiyati Umi, Reagan Muhammad, Darma Surya, Marpaung Blondina, Ginting Andi Raga, Siregar Rizqi Arini, Kambayana Gede, Tejawati Dewa Ayu Kartika, Sindhughosa Dwijo Anargha, Hamijoyo Laniyati, Rahmadi Andri Reza, Wirawan Chevie, Sofiatin Yulia, Kertia Nyoman, Sari Lisa Kurnia, Hellmi Rakhma Yanti, Warlisti Ika Vemilia, Adita Fenda, Werdiningsih Yulyani, Nurudhin Arief, Sunarso Indrayana, Sylvawani Mahriani, Zuaidi Rahmat, Jazmi Dolly, Najirman Najirman, Rikarni Rikarni, Yudha M Agung Pratama, Suarjana Nyoman, Ariadie Dimas, Djallalluddin Djallalluddin, Nugroho Cahyo Wibisono, Rahmawati Lita Diah, Syahriani Femi, Harman Paramitha Puspasari, Elwindy Sarafina, Ongkowijaya Jeffrey Arthur, Januraga Pande Putu, Wardhani Brigitta Dhyah Kunthi, Pradnyani Putu Erma

机构信息

Rheumatology Division Department of Internal Medicine, Faculty of Medicine Universitas Udayana, Ngoerah General Hospital Denpasar, Bali, Indonesia.

Rheumatology Division Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.

出版信息

Int J Rheum Dis. 2025 Jan;28(1):e70014. doi: 10.1111/1756-185X.70014.

DOI:10.1111/1756-185X.70014

PMID:39791539

Abstract

AIM

This study evaluates the prevalence, risk factors, and quality of life of patients with knee osteoarthritis (OA) in the Indonesian population.

METHOD

A cross-sectional study of 3597 adults (≥ 18 years old) was conducted in 2023 involving 15 different cities in Indonesia. Knee OA was classified according to the clinical ACR criteria. The COPCORD questionnaire was used for all subjects. The quality of life (QoL) was assessed using the WOMAC score.

RESULTS

The prevalence of knee OA was 15.0%. Banda Aceh has the highest prevalence of knee OA at 70.79%, whereas Bandung has the lowest (4.18%)-the odds of having knee OA increased with age. The adjusted odds ratio (aOR) were 5.01 (95% CI 2.47-10.15, p < 0.001) for participants aged 40-49 years and 72.19 (95% CI 36.32-143.51, p < 0.001) for participants aged 70 years or over, compared to participants under 40 years. Knee OA was higher among female participants (aOR = 1.91; 95% CI 1.53-2.39, p < 0.001). Married and divorced participants had higher odds of having knee OA compared to those who never married (aORs 2.56 (95% CI 1.37-4.77, p = 0.003) and 2.40 (95% CI 1.23-4.68, p < 0.010), respectively). Knee OA is less likely found among participants with elementary school education background (aOR 0.37; 95% CI 0.22-0.64, p < 0.001) and those with senior high school (aOR 0.49; 95% CI 0.29-0.83, p = 0.007). The total WOMAC score was 25.9 ± 18.7 from all participants, indicating moderate impairment in QoL.

CONCLUSION

The prevalence of knee OA in several urban districts in Indonesia was 15.0%, with most patients having moderate impairment in QoL. Several sociodemographic factors were associated with the odds of having knee OA.

摘要

目的

本研究评估印度尼西亚人群中膝骨关节炎（OA）患者的患病率、危险因素及生活质量。

方法

2023年在印度尼西亚15个不同城市对3597名成年人（≥18岁）进行了一项横断面研究。膝骨关节炎根据美国风湿病学会（ACR）临床标准进行分类。所有受试者均使用COPCORD问卷。使用WOMAC评分评估生活质量（QoL）。

结果

膝骨关节炎的患病率为15.0%。亚齐省的膝骨关节炎患病率最高，为70.79%，而万隆市最低（4.18%）——患膝骨关节炎的几率随年龄增加而升高。与40岁以下的参与者相比，40 - 49岁参与者的调整优势比（aOR）为5.01（95%置信区间2.47 - 10.15，p < 0.001），70岁及以上参与者的调整优势比为72.19（95%置信区间36.32 - 143.51，p < 0.001）。女性参与者的膝骨关节炎患病率更高（aOR = 1.91；95%置信区间1.53 - 2.39，p < 0.001）。已婚和离异参与者患膝骨关节炎的几率高于未婚者（调整优势比分别为2.56（95%置信区间1.37 - 4.77，p = 0.003）和2.40（95%置信区间1.23 - 4.68，p < 0.010））。小学教育背景的参与者（调整优势比0.37；95%置信区间0.22 - 0.64，p < 0.001）和高中教育背景的参与者（调整优势比0.49；95%置信区间0.29 - 0.83，p = 0.007）患膝骨关节炎的可能性较小。所有参与者的WOMAC总分是25.9 ± 18.7，表明生活质量有中度损害。