Li Yuanzhi, Fan Feng, Chen Zhen, Ma Yajing, Liu Chao, Zhang Hang, Fu Yu, Guan Sheng
Department of Neurointervention, The First Affiliated Hospital of Zhengzhou University, 450052, Zhengzhou, Henan, China.
Neurosurg Rev. 2025 Jan 10;48(1):37. doi: 10.1007/s10143-024-03174-6.
To evaluate the safety and efficacy of staged coiling followed by flow diverter (FD) in the treatment of ruptured intracranial aneurysms(RIAs). A retrospective analysis was conducted on 20 patients with RIAs treated with staged coiling followed by FD at a single center, between April 2015 and September 2024. Patient demographics, aneurysm characteristics, clinical and imaging outcomes were reviewed. Aneurysm occlusion was determined using the O'Kelly-Marotta (OKM) grading system. All 20 RIAs underwent successful first-stage coiling. In the second stage, 21 FD were deployed, achieving a 100% success rate. The mean maximum diameter of aneurysms was 10.2 (6.3, 20.7) mm, with a neck width of 6.1 (4.2, 7.8) mm. The interval between the first and second stages was 33.3 ± 23 days. One patient (5%) experienced ischemic complications during the first-stage coiling, but no hemorrhagic complications occurred. In the second stage, FD placement was performed without any hemorrhagic or ischemic complications. All 20 patients (100%) received clinical follow-up with a median follow-up time of 182(172.5,190.5) days.14 patients(70%) underwent available DSA follow-up with a median follow-up time of 184 (158.3, 194.8) days, and the OKM grade B was reported in 1 case (7.1%), grade C in 1 case (7.1%), and grade D in 12 cases (85.7%). No aneurysm recurrence was observed. At the last follow-up, all 20 patients had an mRS score of ≤ 1. Staged coiling followed by FD placement for the treatment of RIAs is a safe and effective approach, with a high technical success rate, low perioperative complication rate, and high aneurysm occlusion rate during follow-up.
评估分期弹簧圈栓塞联合血流导向装置(FD)治疗破裂颅内动脉瘤(RIA)的安全性和有效性。对2015年4月至2024年9月在单中心接受分期弹簧圈栓塞联合FD治疗的20例RIA患者进行回顾性分析。回顾患者的人口统计学资料、动脉瘤特征、临床和影像学结果。使用奥凯利 - 马罗塔(OKM)分级系统确定动脉瘤闭塞情况。所有20例RIA均成功完成第一阶段弹簧圈栓塞。在第二阶段,植入了21枚FD,成功率达100%。动脉瘤的平均最大直径为10.2(6.3,20.7)mm,颈部宽度为6.1(4.2,7.8)mm。第一阶段和第二阶段之间的间隔为33.3±23天。1例患者(5%)在第一阶段弹簧圈栓塞期间出现缺血性并发症,但未发生出血性并发症。在第二阶段,FD植入过程中未出现任何出血性或缺血性并发症。所有20例患者(100%)均接受了临床随访,中位随访时间为182(172.5,190.5)天。14例患者(70%)接受了可行的数字减影血管造影(DSA)随访,中位随访时间为184(158.3,194.8)天,OKM分级报告为B级1例(7.1%),C级1例(7.1%),D级12例(85.7%)。未观察到动脉瘤复发。在最后一次随访时,所有20例患者的改良Rankin量表(mRS)评分均≤1。分期弹簧圈栓塞联合FD植入治疗RIA是一种安全有效的方法,技术成功率高,围手术期并发症发生率低,随访期间动脉瘤闭塞率高。