前列腺素对脂多糖刺激的小鼠白细胞产生集落刺激因子的调节作用。
Prostaglandin regulation of colony-stimulating factor production by lipopolysaccharide-stimulated murine leukocytes.
作者信息
Moore R N, Urbaschek R, Wahl L M, Mergenhagen S E
出版信息
Infect Immun. 1979 Nov;26(2):408-14. doi: 10.1128/iai.26.2.408-414.1979.
Abstract
The production of colony-stimulating factor by lipopolysaccharide-stimulated murine peritoneal leukocytes and their adherent subpopulations (greater than 80% macrophages) was markedly enhanced by indomethacin at concentrations sufficient to block prostaglandin E synthesis. Addition of physiological concentrations of E-series prostaglandins reversed this enhancing effect of indomethacin in a dose-dependent manner. These results indicate that colony-stimulating factor production by stimulated leukocytes is regulated by E-series prostaglandins and suggest that prostaglandins function to limit myelopoiesis by inhibiting colony-stimulating factor production and concomitantly the induction of cell proliferation.
摘要
脂多糖刺激的小鼠腹腔白细胞及其贴壁亚群（超过80%为巨噬细胞）产生集落刺激因子的能力，在足以阻断前列腺素E合成的吲哚美辛浓度下显著增强。添加生理浓度的E系列前列腺素可剂量依赖性地逆转吲哚美辛的这种增强作用。这些结果表明，受刺激白细胞产生集落刺激因子受E系列前列腺素调控，并提示前列腺素通过抑制集落刺激因子产生以及随之而来的细胞增殖诱导，发挥限制骨髓生成的作用。
相似文献
1
Prostaglandin regulation of colony-stimulating factor production by lipopolysaccharide-stimulated murine leukocytes.前列腺素对脂多糖刺激的小鼠白细胞产生集落刺激因子的调节作用。
Infect Immun. 1979 Nov;26(2):408-14. doi: 10.1128/iai.26.2.408-414.1979.
2
The effect of indomethacin on colony-stimulating-factor production by the lung.
Prostaglandins Leukot Essent Fatty Acids. 1991 Jan;42(1):57-60. doi: 10.1016/0952-3278(91)90067-f.
3
Regulation of macrophage and granulocyte proliferation. Specificities of prostaglandin E and lactoferrin.巨噬细胞和粒细胞增殖的调节。前列腺素E和乳铁蛋白的特异性。
J Exp Med. 1979 Aug 1;150(2):277-92. doi: 10.1084/jem.150.2.277.
4
Role of prostaglandin E and interferon in secretion of colony-stimulating factor by murine macrophages after in vitro treatment with biological response modifiers.前列腺素E和干扰素在生物反应调节剂体外处理后小鼠巨噬细胞分泌集落刺激因子中的作用
Int J Immunopharmacol. 1984;6(5):407-18. doi: 10.1016/0192-0561(84)90078-x.
5
Induction of prostaglandin E synthesis in normal and neoplastic macrophages: role for colony-stimulating factor(s) distinct from effects on myeloid progenitor cell proliferation.正常及肿瘤性巨噬细胞中前列腺素E合成的诱导：集落刺激因子不同于对髓系祖细胞增殖影响的作用。
Proc Natl Acad Sci U S A. 1979 May;76(5):2326-30. doi: 10.1073/pnas.76.5.2326.
6
Limitation of excessive myelopoiesis by the intrinsic modulation of macrophage-derived prostaglandin E.巨噬细胞衍生的前列腺素E的内在调节对过度骨髓生成的限制作用
Science. 1978 Feb 3;199(4328):552-5. doi: 10.1126/science.304600.
7
The effect of lipopolysaccharide on the production of GM-EA, GM-CSA, and PGE2 by human monocyte-derived lipid-containing macrophages.
Exp Hematol. 1988 Jun;16(5):349-54.
8
Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.人血单核细胞和小鼠腹腔巨噬细胞产生前列腺素E
J Exp Med. 1978 Mar 1;147(3):952-7. doi: 10.1084/jem.147.3.952.
9
10
Lactoferrin acts on I-A and I-E/C antigen+ subpopulations of mouse peritoneal macrophages in the absence of T lymphocytes and other cell types to inhibit production of granulocyte-macrophage colony stimulatory factors in vitro.乳铁蛋白在无T淋巴细胞和其他细胞类型的情况下作用于小鼠腹腔巨噬细胞的I-A和I-E/C抗原阳性亚群，以在体外抑制粒细胞-巨噬细胞集落刺激因子的产生。
J Immunol. 1984 Jul;133(1):306-14.
引用本文的文献
1
Autocrine-paracrine prostaglandin E signaling restricts TLR4 internalization and TRIF signaling.自分泌旁分泌前列腺素 E 信号限制 TLR4 内化和 TRIF 信号。
Nat Immunol. 2018 Dec;19(12):1309-1318. doi: 10.1038/s41590-018-0243-7. Epub 2018 Nov 5.
2
Role of lipopolysaccharide in regulating colony-stimulating factor-dependent macrophage proliferation in vitro.脂多糖在体外调节集落刺激因子依赖性巨噬细胞增殖中的作用。
Infect Immun. 1980 Dec;30(3):797-804. doi: 10.1128/iai.30.3.797-804.1980.
3
In vitro suppression of myelopoiesis by adherent murine splenocytes in experimental disseminated histoplasmosis.实验性播散性组织胞浆菌病中贴壁小鼠脾细胞对骨髓生成的体外抑制作用
Am J Pathol. 1983 Mar;110(3):247-53.
4
Regulation of murine macrophage Ia-antigen expression by products of activated spleen cells.活化脾细胞产物对小鼠巨噬细胞Ia抗原表达的调节
J Exp Med. 1980 Dec 1;152(6):1734-44. doi: 10.1084/jem.152.6.1734.
5
6
Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.白细胞介素1刺激成纤维细胞产生粒细胞-巨噬细胞集落刺激活性和前列腺素E2。
J Clin Invest. 1986 Jun;77(6):1857-63. doi: 10.1172/JCI112512.
7
Rabbit lymphocyte factors modulate prostaglandin biosynthesis in alveolar macrophages.兔淋巴细胞因子调节肺泡巨噬细胞中前列腺素的生物合成。
Immunology. 1985 Jan;54(1):155-61.
8
Development of antitumor activity in LPS-stimulated mouse granuloma macrophages. Regulation by eicosanoids.
Inflammation. 1986 Jun;10(2):195-204. doi: 10.1007/BF00916001.
9
Prostaglandins in experimental syphilis: treponemes stimulate adherent spleen cells to secrete prostaglandin E2, and indomethacin upregulates immune functions.实验性梅毒中的前列腺素：梅毒螺旋体刺激贴壁脾细胞分泌前列腺素E2，吲哚美辛上调免疫功能。
Infect Immun. 1991 Jan;59(1):143-9. doi: 10.1128/iai.59.1.143-149.1991.
10
Cyclic AMP inhibition of lipopolysaccharide-induced restriction of Legionella pneumophila growth in macrophage cultures.环磷酸腺苷对脂多糖诱导的巨噬细胞培养物中嗜肺军团菌生长限制的抑制作用。
Infect Immun. 1992 May;60(5):1936-40. doi: 10.1128/iai.60.5.1936-1940.1992.
本文引用的文献
1
The induction of clones of normal mast cells by a substance from conditioned medium.一种来自条件培养基的物质对正常肥大细胞克隆的诱导作用。
Exp Cell Res. 1966 Oct;43(3):553-63. doi: 10.1016/0014-4827(66)90026-7.
2
Human bone marrow colony growth in agar-gel.人骨髓在琼脂凝胶中的集落生长。
J Cell Physiol. 1970 Aug;76(1):77-84. doi: 10.1002/jcp.1040760111.
3
Colony-stimulating factor and inhibitor levels in acute granulocytic leukemia.急性粒细胞白血病中的集落刺激因子和抑制因子水平
Blood. 1971 Aug;38(2):143-52.
4
Acute antigen-induced elevation of serum colony stimulating factor (CFS) levels.急性抗原诱导的血清集落刺激因子（CFS）水平升高。
Immunology. 1971 Sep;21(3):427-36.
5
Chemical, physical, biological properties of a lipopolysaccharide from Escherichia coli K-235.大肠杆菌K-235脂多糖的化学、物理和生物学性质
Biochemistry. 1967 Aug;6(8):2363-72. doi: 10.1021/bi00860a011.
6
In vitro production of colony-stimulating activity. I. Exposure of mouse peritoneal cells to endotoxin.
Cell Tissue Kinet. 1974 Jan;7(1):19-30. doi: 10.1111/j.1365-2184.1974.tb00395.x.
7
Effect of endotoxin on the production of colony-stimulating factor by human monocytes and macrophages.
J Cell Physiol. 1974 Oct;84(2):193-6. doi: 10.1002/jcp.1040840205.
8
Role of cyclic adenosine 3',5'-monophosphate in lymphocyte mitogenesis.环磷酸腺苷在淋巴细胞有丝分裂中的作用。
J Immunol. 1974 Jul;113(1):151-61.
9
Human lymphocytic metabolism. Effects of cyclic and noncyclic nucleotides on stimulation by phytohemagglutinin.人类淋巴细胞代谢。环核苷酸和非环核苷酸对植物血凝素刺激的影响。
J Clin Invest. 1971 Feb;50(2):442-8. doi: 10.1172/JCI106511.
10
The growth of mouse bone marrow cells in vitro.小鼠骨髓细胞的体外生长
Aust J Exp Biol Med Sci. 1966 Jun;44(3):287-99. doi: 10.1038/icb.1966.28.
Zotero 插件