Gastesi Irati, Domínguez-Rodríguez Sara, Le Prevost Marthe, Ramírez Andrea, Giaquinto Carlo, Mesa María Lucía, Ballesteros Alvaro, Jackson Charlotte, Vásquez-Hoyos Pablo, Alvarez Moreno Carlos, Grasa Carlos, Epalza Cristina, Soriano-Arandes Antoni, Moraleda Cinta, Tagarro Alfredo
From the Innovation and Global Pediatric Infectious Disease, Biomedical Research Foundation of the University Hospital 12 de Octubre (FIBH12O), Instituto de Investigación Hospital 12 de Octubre (imas12), Madrid, Spain.
Universidad Europea, Madrid, Spain.
Pediatr Infect Dis J. 2025 May 1;44(5):439-441. doi: 10.1097/INF.0000000000004684. Epub 2025 Jan 9.
In this prospective cohort study with 2326 hospitalized children and young people with coronavirus disease 2019 in Spain and Colombia, 36.4% had comorbidities. Asthma, recurrent wheezing, chronic neurological, cardiac and pulmonary diseases significantly increased the risk of severe outcomes such as death, mechanical ventilation and intensive care unit admission. The incremental risk with additional comorbidities underscores the importance of targeted vaccination strategies for vulnerable children and young people populations.
在这项针对西班牙和哥伦比亚2326名住院的2019冠状病毒病儿童和青少年的前瞻性队列研究中，36.4%的患者患有合并症。哮喘、复发性喘息、慢性神经、心脏和肺部疾病显著增加了死亡、机械通气和入住重症监护病房等严重后果的风险。合并症增多带来的额外风险凸显了针对弱势儿童和青少年群体采取有针对性的疫苗接种策略的重要性。
