Temporal trends of transcatheter aortic valve replacement outcomes in a high-volume center from China.

Since the first transcatheter aortic valve replacement (TAVR) was performed in China in 2010, TAVR has developed rapidly. However, the temporal trends in the 1-year prognosis after TAVR in China have not been described. This study enrolled patients treated at a high-volume Chinese TAVR center, West China Hospital, between 2015 and 2022, to analyze and characterize the temporal trends in 1-year outcomes. After multivariate adjustment, the 30-day mortality, 1-year all-cause mortality, 1-year cardiac mortality, and 1-year permanent pacemaker implantation rates showed a significantly decreasing trend (adjusted p for trend < 0.05). The 1-year major adverse cardiovascular event and 1-year stroke incident rate also decreased but did not reach significance. In conclusion, this study, for the first time, reveals a declining trend in adverse prognosis among patients who underwent TAVR in China.