Xiong Yan, Pu Di
Department of Neurology and Geriatrics, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China.
Medicine (Baltimore). 2025 Jan 10;104(2):e41135. doi: 10.1097/MD.0000000000041135.
The aim was to explore the application value of dynamic electroencephalography (EEG) combined with brainstem auditory evoked potential (BAEP) in evaluating the degree of vascular stenosis and prognosis in patients with ischemic stroke (IS). This was a retrospective study using clinical data of patients with IS admitted to the First Affiliated Hospital of Chongqing Medical and Pharmaceutical College from March 2020 to March 2022. The degree of vascular stenosis and prognosis of patients were analyzed. In addition, the correlation between EEG, BAEP examination and the degree of vascular stenosis was studied. A total of 105 patients met the inclusion and exclusion criteria were included in this study. Among them, 43 cases were mild stenosis, 42 cases were moderate stenosis, and 20 cases were severe stenosis; 32 cases had poor prognosis and 73 cases had good prognosis. The quantitative electroencephalogram index (delta + theta)/(alpha + beta) ratio (DTABR), peak latency (PL) of waves I and V, and interval PL (IPL) of waves III to V and I to V in patients with moderate stenosis or severe stenosis were significantly higher than those in patients with mild stenosis (P < .05). Moreover, the above indicators were significantly higher in patients with severe stenosis than in patients with moderate stenosis (P < .05). According to Spearman test, the patients' DTABR, PL of wave I and wave V, and IPL of wave III to V and wave I to V were positively correlated with the degree of vascular stenosis, respectively (P < .05). The DTABR, wave I, wave V, wave III to V, and wave I to V of patients with poor prognosis were higher than those with good prognosis (P < .05). The DTABR, PL of waves I and V, and IPL of waves III to V and I to V in patients with poor prognosis were significantly higher than those in patients with good prognosis (P < .05). EEG combined with BAEP has high value in assessing the degree of vascular stenosis and prognosis in patients with IS, which provides a reference basis for clinical development or adjustment of subsequent intervention plans.
目的是探讨动态脑电图（EEG）联合脑干听觉诱发电位（BAEP）在评估缺血性脑卒中（IS）患者血管狭窄程度及预后中的应用价值。这是一项回顾性研究，采用了2020年3月至2022年3月在重庆医药高等专科学校附属第一医院住院的IS患者的临床资料。分析了患者的血管狭窄程度及预后情况。此外，研究了EEG、BAEP检查与血管狭窄程度之间的相关性。本研究共纳入105例符合纳入和排除标准的患者。其中，轻度狭窄43例，中度狭窄42例，重度狭窄20例；预后不良32例，预后良好73例。中度狭窄或重度狭窄患者的定量脑电图指数（δ+θ）/（α+β）比值（DTABR）、波I和波V的峰潜伏期（PL）以及波III至V和波I至V的峰间潜伏期（IPL）显著高于轻度狭窄患者（P<0.05）。此外，重度狭窄患者的上述指标显著高于中度狭窄患者（P<0.05）。根据Spearman检验，患者的DTABR、波I和波V的PL以及波III至V和波I至V的IPL分别与血管狭窄程度呈正相关（P<0.05）。预后不良患者的DTABR、波I、波V、波III至V和波I至V均高于预后良好患者（P<0.05）。预后不良患者的DTABR、波I和波V的PL以及波III至V和波I至V的IPL显著高于预后良好患者（P<0.05）。EEG联合BAEP在评估IS患者血管狭窄程度及预后方面具有较高价值，可为临床制定或调整后续干预方案提供参考依据。
