Xu Qiang, Li Wen, Zheng Xianglong, Lin Lisong
Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, National Regional Medical Center, Binhai Campus of The First Affiliated Hospital, Fuzhou, Fujian 350005, PR China.
Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Fujian Medical University, National Regional Medical Center, Binhai Campus of The First Affiliated Hospital, Fuzhou, Fujian 350005, PR China.
J Stomatol Oral Maxillofac Surg. 2025 Jun;126(3S):102225. doi: 10.1016/j.jormas.2025.102225. Epub 2025 Jan 8.
The thin anterolateral thigh flap (tALTF) is gaining attention in reconstructive surgery due to its aesthetic and functional advantages. However, its clinical safety and outcomes compared to other commonly used free soft flaps (CUFSFs) remain unclear.
Studies were systematically searched from PubMed, EMBASE, Medline, Cochrane, Web of Science, and China National Knowledge Infrastructure Database up to November 2, 2024. Flap failure, donor and recipient site morbidity, secondary salvage surgery, and patient satisfaction were evaluated.
A total of 416 cases from 7 studies were included in our analysis. No significant difference was observed between the two groups in flap failure and secondary salvage surgery. However, tALTF showed significant advantages over CUFSFs in skin grafting, donor and recipient site morbidity, and patient satisfaction.
This meta-analysis highlights the clinical safety and superior outcomes of tALTF compared to CUFSFs in reconstructive surgery, suggesting its viability as a preferred option for surgeons. However, the retrospective design of the included studies and limited sample sizes necessitate further large-scale prospective studies to validate these results.
由于具有美学和功能优势，股前外侧超薄皮瓣（tALTF）在重建手术中日益受到关注。然而，与其他常用的游离软组织瓣（CUFSFs）相比，其临床安全性和效果仍不明确。
截至2024年11月2日，从PubMed、EMBASE、Medline、Cochrane、Web of Science和中国知网数据库系统检索相关研究。评估皮瓣失败情况、供区和受区并发症、二次挽救手术以及患者满意度。
我们的分析纳入了7项研究中的416例病例。两组在皮瓣失败和二次挽救手术方面未观察到显著差异。然而，tALTF在植皮、供区和受区并发症以及患者满意度方面比CUFSFs具有显著优势。
这项荟萃分析突出了tALTF在重建手术中与CUFSFs相比的临床安全性和更优效果，表明其作为外科医生首选方案的可行性。然而，纳入研究的回顾性设计和样本量有限，需要进一步开展大规模前瞻性研究来验证这些结果。
