McAuley R, Lull R, Ice R
Eur J Nucl Med. 1985;10(1-2):60-2. doi: 10.1007/BF00261765.
Following receipt of fission product 99mTc-generators, results of radionuclide purity analysis, performed within 30 min after the first elution, demonstrated detectable levels of a contaminate radionuclide not previously reported. Gamma spectroscopy and half-life determinations confirmed the presence of 82Br. Bromine-82 activity, in eluates from the first elution of 30 generators, received weekly during a 7-month period, ranged from 0.22 microCi (8.235 kBq) to 0.67 microCi (24.68 kBq) per eluate. The ratio of 99Mo to 99mTc ranged from 0.13 nCi to 0.39 nCi per mCi 99mTc. The presence of 82Br in 99mTc-generator eluate resulted in falsely elevated 99Mo assay determinations using whole vial 99Mo assay procedures. For every 0.1 microCi 82Br present in 99mTc eluate the 99Mo assay results were elevated by 1 microCi. Gamma spectroscopy of eluates from additional elutions of these generators failed to detect the presence of 82Br demonstrating the displacement of monovalent bromine anions from the alumina column during the first elution.
在收到裂变产物99mTc发生器后，首次洗脱后30分钟内进行的放射性核素纯度分析结果显示，存在一种此前未报告的可检测水平的污染性放射性核素。γ能谱分析和半衰期测定证实了82Br的存在。在7个月期间每周接收的30个发生器首次洗脱液中的溴-82活度，每洗脱液范围为0.22微居里（8.235千贝克勒尔）至0.67微居里（24.68千贝克勒尔）。每毫居里99mTc中99Mo与99mTc的比例范围为0.13纳居里至0.39纳居里。99mTc发生器洗脱液中82Br的存在导致使用全瓶99Mo分析程序时99Mo分析测定结果出现错误升高。99mTc洗脱液中每存在0.1微居里82Br，99Mo分析结果就升高1微居里。对这些发生器额外洗脱液的γ能谱分析未能检测到82Br的存在，这表明在首次洗脱过程中一价溴阴离子从氧化铝柱上被置换下来。
