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基于网络的神经心理功能无监督评估的预测价值

Predictive value of an unsupervised web-based assessment of the neuropsychological function.

作者信息

Werrmann Michelle, Gür-Tok Yesim, Eid Michael, Niedeggen Michael

机构信息

Division of Experimental Psychology and Neuropsychology, Department of Education and Psychology, Freie Universität Berlin, Habelschwerdter Allee 45, 14195, Berlin, Germany.

Division of Methods and Evaluation, Department of Education and Psychology, Freie Universität Berlin, Berlin, Germany.

出版信息

Sci Rep. 2025 Jan 10;15(1):1645. doi: 10.1038/s41598-025-85614-x.

Abstract

Neuropsychological assessment has to consider the subjective and objective functional deficits of help-seeking individuals in several cognitive domains. Due to time constraints in clinical practice, several web-based approaches have been developed. The current study examined whether functional deficits in the mnestic and attentive domain can be predicted based on an unsupervised self-administered online assessment neuropsychological online screening (NOS): This screening includes self-reports and psychometric memory tests (face-name association, visual short-term memory). Data of help-seeking individuals (n = 213, mean age: 48.2 years) running an extensive in-person assessment were analyzed. A functional deficit in at least one cognitive domain was detected in 48 individuals. This classification was supported by the preceding online screening (sensitivity = 0.75, specificity = 0.80), and a linear regression model identified two significant predictors (free recall performance, form discrimination in visual short-term memory). The predictive quality was enhanced for individuals with selective deficits in the mnestic domain (n = 23: sensitivity = 0.78 and specificity = 0.78) as compared to the attentive domain (n = 25: sensitivity = 0.68 and specificity = 0.75). Our results show that a neuropsychological in-person assessment cannot be replaced by an unsupervised self-administered online test. However, a specific pattern of results in the online test might indicate the necessity of an extensive assessment in help-seeking individuals.

摘要

神经心理学评估必须考虑求助个体在多个认知领域的主观和客观功能缺陷。由于临床实践中的时间限制,已经开发了几种基于网络的方法。本研究调查了是否可以基于无监督的自我管理在线评估——神经心理学在线筛查(NOS)来预测记忆和注意力领域的功能缺陷:该筛查包括自我报告和心理测量记忆测试(面孔-名字联想、视觉短期记忆)。对进行了广泛面对面评估的求助个体(n = 213,平均年龄:48.2岁)的数据进行了分析。在48名个体中检测到至少一个认知领域存在功能缺陷。这种分类得到了之前在线筛查的支持(敏感性 = 0.75,特异性 = 0.80),并且线性回归模型确定了两个显著的预测因素(自由回忆表现、视觉短期记忆中的形状辨别)。与注意力领域(n = 25:敏感性 = 0.68,特异性 = 0.75)相比,记忆领域存在选择性缺陷的个体(n = 23:敏感性 = 0.78,特异性 = 0.78)的预测质量有所提高。我们的结果表明,神经心理学面对面评估不能被无监督的自我管理在线测试所取代。然而,在线测试中的特定结果模式可能表明求助个体需要进行广泛评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5be3/11724069/82e8ba1782c5/41598_2025_85614_Fig1_HTML.jpg

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