Redjeki Sarah Gustia, Hulwana Alfa Fildzah, Aulia Rizqa Nurul, Maya Ira, Chaerunisaa Anis Yohana, Sriwidodo Sriwidodo
Undergraduate Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.
Master Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.
Molecules. 2025 Jan 3;30(1):160. doi: 10.3390/molecules30010160.
Sacha inchi ( L.), an oilseed native to the Peruvian rainforest, has garnered attention for its valuable components and its potential applications in the food, pharmaceutical, and nutraceutical industries. Sacha inchi oil is rich in fatty acids, particularly omega-3, omega-6, and omega-9, along with antioxidants such as tocopherols, which collectively contribute to cardiovascular health, antioxidant, anti-inflammatory, antiproliferative, and neuroprotective effects. The susceptibility of the oil to oxidation poses significant challenges for both storage and processing, making it essential to employ microencapsulation technologies to preserve its integrity and extend shelf life. This paper aims to provide a review of the therapeutic potential, extraction methods, and microencapsulation strategies for enhancing the oil's stability and bioavailability. Optimizing both extraction processes and encapsulation strategies would enhance the oil's stability and bioavailability, enabling it to be more effectively utilized in functional foods and therapeutic applications across the nutraceutical and pharmaceutical fields.
印加果(Sacha inchi (L.))是一种原产于秘鲁雨林的油料作物,因其富含珍贵成分以及在食品、制药和营养保健品行业的潜在应用而备受关注。印加果油富含脂肪酸,尤其是欧米伽-3、欧米伽-6和欧米伽-9,还含有生育酚等抗氧化剂,这些成分共同对心血管健康、抗氧化、抗炎、抗增殖和神经保护作用有贡献。该油对氧化的敏感性给储存和加工都带来了重大挑战,因此采用微胶囊技术来保持其完整性并延长保质期至关重要。本文旨在综述印加果油的治疗潜力、提取方法以及提高其稳定性和生物利用度的微胶囊策略。优化提取工艺和包封策略将提高该油的稳定性和生物利用度,使其能够更有效地应用于营养保健品和制药领域的功能性食品和治疗应用中。