Nešić Aleksandra, Lučić Milica, Vesković Jelena, Mandić Ljiljana Janković, Momčilović Milan, Miletić Andrijana, Onjia Antonije
Vinča Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12-14, 11351 Belgrade, Serbia.
Innovation Center of the Faculty of Technology and Metallurgy, 11120 Belgrade, Serbia.
Foods. 2024 Dec 25;14(1):18. doi: 10.3390/foods14010018.
Chocolate is one of the most popular and widely consumed confectionery products. However, elevated cadmium (Cd) content in this commodity threatens food safety and human health. It is crucial to monitor the presence of Cd in chocolate and to evaluate its associated health risks. This study assessed the Cd levels in milk and dark chocolates from the Serbian market ( = 155). Cadmium concentrations varied between 0.010 and 0.29 mg/kg. The obtained values were used to evaluate the hazard quotient (HQ) and cancer risk (CR). The estimated weekly intakes (EWIs) were below the tolerable limits for all samples. However, in some samples, the EWI reached 60.9% and 63.5% of the tolerable limit for toddlers and other children, respectively. No health risk was found based on the HQ. On the other hand, based on CR values, all chocolate products can be classified as posing a moderate risk. The Monte Carlo simulation indicated that toddlers and other children were more exposed to non-carcinogenic risk, whereas vegetarians, adults, pregnant women, and other children were more exposed to cancer risk. Sensitivity analysis indicates that body weight, exposure frequency, and ingestion rate are the most influential factors for non-cancer and cancer health risks.
巧克力是最受欢迎且消费广泛的糖果产品之一。然而,该商品中镉(Cd)含量升高威胁食品安全和人类健康。监测巧克力中镉的存在并评估其相关健康风险至关重要。本研究评估了塞尔维亚市场上牛奶巧克力和黑巧克力中的镉含量(n = 155)。镉浓度在0.010至0.29毫克/千克之间变化。所得值用于评估危害商数(HQ)和癌症风险(CR)。所有样品的估计每周摄入量(EWIs)均低于耐受限度。然而,在一些样品中,EWI分别达到幼儿和其他儿童耐受限度的60.9%和63.5%。基于HQ未发现健康风险。另一方面,基于CR值,所有巧克力产品可归类为具有中度风险。蒙特卡洛模拟表明,幼儿和其他儿童更容易受到非致癌风险的影响,而素食者、成年人、孕妇和其他儿童更容易受到癌症风险的影响。敏感性分析表明,体重、接触频率和摄入率是影响非癌症和癌症健康风险的最主要因素。