Wei Yaohui, Wang Yating, Yuan Yonggui, Chen Jue
Department of Clinical Psychology, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
Department of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Foods. 2024 Dec 31;14(1):74. doi: 10.3390/foods14010074.
Celiac disease (CD) and eating disorders (EDs) are complex chronic conditions in adolescents, sharing symptoms such as weight change, malnutrition, and gastrointestinal symptoms. CD, an autoimmune disorder triggered by gluten ingestion, is managed through a strict gluten-free diet that can unintentionally foster disordered eating behaviors due to dietary restrictions. Conversely, EDs may mask and complicate CD symptoms, leading to diagnostic delays and treatment challenges. Evidence reveals an increased risk of EDs in CD individuals and vice versa, indicating a potential bidirectional relationship. This review explores the mechanisms and clinical implications of this interplay and proposes integrated screening and care strategies to improve the quality of life for individuals with both conditions.
乳糜泻（CD）和饮食失调（EDs）是青少年时期复杂的慢性疾病，具有体重变化、营养不良和胃肠道症状等共同症状。CD是一种由摄入麸质引发的自身免疫性疾病，通过严格的无麸质饮食进行管理，这种饮食由于饮食限制可能无意中助长饮食紊乱行为。相反，EDs可能掩盖CD症状并使其复杂化，导致诊断延迟和治疗挑战。有证据表明，患有CD的个体患EDs的风险增加，反之亦然，这表明存在潜在的双向关系。本综述探讨了这种相互作用的机制和临床意义，并提出了综合筛查和护理策略，以提高患有这两种疾病的个体的生活质量。
