Neto Luiz Claudio Barreto Silva, Enriquez-Martinez Oscar Geovanny, Grippa Wesley Rocha, Marcarini Julia Anhoque Cavalcanti, Santos Thayná Borges, Mawandji Nina Bruna de Souza, Gomes Karoline Neumann, Schuab Sara Isabel Pimentel de Carvalho, Minarini Etreo Junior Carneiro da Silva, Nunes Karolini Zuqui, Bolsoni-Lopes Andressa, Lopes-Júnior Luís Carlos
Graduate Program in Public Health, Universidade Federal do Espírito Santo, Vitória 29075-910, ES, Brazil.
Graduate Program in Nutrition and Health, Universidade Federal do Espírito Santo, Vitória 29075-910, ES, Brazil.
Nutrients. 2025 Jan 2;17(1):168. doi: 10.3390/nu17010168.
BACKGROUND/OBJECTIVES: Cancer, a leading cause of mortality globally and in Brazil, is influenced by environmental and behavioral factors, often linked to nutritional deficiencies such as low body mass index and muscle wasting, exacerbating prognostic outcomes and mortality rates. Timely nutritional interventions during chemotherapy are pivotal, necessitating continuous nutritional assessment for effective patient care management. This study aimed to assess the nutritional status of non-metastatic cancer patients undergoing chemotherapy and identify factors influencing their nutritional status. Patient evaluation involved sociodemographic data, clinical profiles, anthropometric measurements, blood biochemical analyses, and nutritional status classification employing the Patient-Generated Subjective Global Assessment (PG-SGA) criteria. Statistical analysis was performed using R software.
Suspected malnutrition was identified in 5.81% of patients, with a significant association observed with gender, indicating a higher prevalence among men. Cancer stages II and III, along with a positive family history, correlated with heightened risk of malnutrition. Patients with suspected malnutrition exhibited older age, lower weight, body mass index (BMI), and reduced circumferences, underscoring the necessity of comprehensive nutritional assessment for optimized patient management during treatment.
This study underscores a notable prevalence of malnutrition, particularly among patients with lower weight and BMI, affirming the reliability of PG-SGA criteria.
背景/目的:癌症是全球及巴西主要的死亡原因之一,受环境和行为因素影响,这些因素常与诸如低体重指数和肌肉消耗等营养缺乏相关,会加剧预后结果和死亡率。化疗期间及时的营养干预至关重要,需要持续进行营养评估以有效管理患者护理。本研究旨在评估接受化疗的非转移性癌症患者的营养状况,并确定影响其营养状况的因素。患者评估包括社会人口统计学数据、临床特征、人体测量、血液生化分析以及采用患者主观全面评定法(PG-SGA)标准进行营养状况分类。使用R软件进行统计分析。
5.81%的患者被判定为疑似营养不良,观察到与性别存在显著关联,表明男性患病率更高。癌症II期和III期以及家族史阳性与营养不良风险增加相关。疑似营养不良的患者年龄较大、体重、体重指数(BMI)较低且周长减小,这突出了在治疗期间进行全面营养评估以优化患者管理的必要性。
本研究强调营养不良的患病率显著,尤其是体重和BMI较低的患者,证实了PG-SGA标准的可靠性。