Cristian Adrian, Keole Nandita, Orada Romer, Seo Jayhyun, Guerrina Austin, Maharaj Arun
Cancer Rehabilitation, Miami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.
Department of Physical Medicine and Rehabilitation, Mayo Clinic Hospital, Phoenix, AZ 85054, USA.
Cancers (Basel). 2024 Dec 24;17(1):6. doi: 10.3390/cancers17010006.
Sarcomas are a rare, complex group of malignancies characterized by numerous clinical and pathological features. Sarcomas originate from various tissues such as fat, muscle, bone, nerves, blood vessels and connective tissues. Typically, the treatment of sarcomas consists of surgery, chemotherapy, and radiation therapy. The location, type, stage, and treatment of sarcomas contribute to the development of physical impairments affecting joint and limb function, peripheral nerves, strength, and mobility, diminishing physical function and quality of life. Traditionally, rehabilitative therapy has been implemented after cancer treatment to help improve physical impairments imparted from cancer therapy. Recent work in rehabilitative medicine has explored the implementation of rehabilitative therapy prior to beginning cancer treatment (pre-habilitation) to help mitigate the detrimental physical consequences seen in sarcoma patients.
The objective of this narrative review is to examine the physical impairments affecting sarcoma patients after cancer therapy and the impact of rehabilitative medicine on physical function and quality of life when implemented before and after cancer treatment.
肉瘤是一类罕见且复杂的恶性肿瘤，具有众多临床和病理特征。肉瘤起源于各种组织，如脂肪、肌肉、骨骼、神经、血管和结缔组织。通常，肉瘤的治疗包括手术、化疗和放疗。肉瘤的位置、类型、分期和治疗会导致影响关节和肢体功能、周围神经、力量和活动能力的身体损伤，从而降低身体功能和生活质量。传统上，康复治疗在癌症治疗后实施，以帮助改善癌症治疗所致的身体损伤。康复医学的最新研究探讨了在开始癌症治疗之前实施康复治疗（预康复），以帮助减轻肉瘤患者出现的有害身体后果。
本叙述性综述的目的是研究癌症治疗后影响肉瘤患者的身体损伤，以及康复医学在癌症治疗前后实施时对身体功能和生活质量的影响。
