Gerlich Moritz, Schmid Andreas, Greiner Thomas, Kray Stefan
Institute of Smart Systems and Services, Pforzheim University, 75175 Pforzheim, Germany.
Sensors (Basel). 2024 Dec 29;25(1):141. doi: 10.3390/s25010141.
Multispectral imaging (MSI) enables non-invasive tissue differentiation based on spectral characteristics and has shown great potential as a tool for surgical guidance. However, adapting MSI to open surgeries is challenging. Systems that rely on light sources present in the operating room experience limitations due to frequent lighting changes, which distort the spectral data and require countermeasures such as disruptive recalibrations. On the other hand, MSI systems that rely on dedicated lighting require external light sources, such as surgical lights, to be turned off during open surgery settings. This disrupts the surgical workflow and extends operation times. To this end, we present an approach that addresses these issues by combining active illumination with smart background suppression. By alternately capturing images with and without a modulated light source at a desired wavelength, we isolate the target signal, enabling artifact-free spectral scanning. We demonstrate the performance of our approach using a smart pixel camera, emphasizing its signal-to-noise ratio (SNR) advantage over a conventional high-speed camera. Our results show that accurate reflectance measurements can be achieved in clinical settings with high background illumination. Medical application is demonstrated through the estimation of blood oxygenation, and its suitability for open surgeries is discussed.
多光谱成像(MSI)能够基于光谱特征实现非侵入性组织区分,并已显示出作为手术引导工具的巨大潜力。然而,使MSI适用于开放手术具有挑战性。依赖手术室现有光源的系统由于频繁的光照变化而受到限制,这会扭曲光谱数据并需要诸如破坏性重新校准等对策。另一方面,依赖专用照明的MSI系统在开放手术环境中需要关闭外部光源,如手术灯。这会扰乱手术流程并延长手术时间。为此,我们提出一种通过将主动照明与智能背景抑制相结合来解决这些问题的方法。通过在所需波长下交替使用调制光源和不使用调制光源捕获图像,我们分离出目标信号,实现无伪影光谱扫描。我们使用智能像素相机展示了我们方法的性能,强调了其相对于传统高速相机的信噪比(SNR)优势。我们的结果表明,在高背景照明的临床环境中可以实现准确的反射率测量。通过估计血液氧合展示了医学应用,并讨论了其在开放手术中的适用性。