Pfeifer Jochen, Poryo Martin, Gheibeh Anas, Rentzsch Axel, Abdul-Khaliq Hashim
Department of Pediatric Cardiology, Saarland University Medical Center, D-66421 Homburg, Germany.
J Clin Med. 2024 Dec 28;14(1):113. doi: 10.3390/jcm14010113.
Systemic-to-pulmonary collaterals (SPCs) are common in congenital heart disease (CHD). Particularly in single ventricle anatomy and Fontan circulation, SPC can both complicate the postoperative course and lead to clinical deterioration in the long term. The treatment of SPC is controversial. The aim of our study was (1) to retrospectively analyse patients who underwent SPC embolization using Concerto™ Helix nylon-fibred microcoils (CHMs) and (2) to describe the interventional technique. In this single-centre retrospective observational cohort study, we analysed clinical and imaging data of all patients who underwent transcatheter embolization of SPCs using CHMs from January 2016 to December 2023. In 38 consecutive patients (65.8% male, median age 41 months, range 2-490), a total number of 141 CHMs had been implanted into 64 SPCs in 49 procedures. The majority were arterial SPCs ( = 59/64) originating from the thoracic aorta or its branches; 5/64 were veno-venous SPCs. Primary closure succeeded in all procedures. The CHM diameters ranged from 3 to 8 mm, with 5 mm being the most commonly used diameter. The mean coil/SPC ratio was 2.6 (range 1.3-5.3). CHM implantation was performed via four French sheaths. Both detachment and stable positioning were simple and safe. Neither non-target embolization nor coil migration occurred. One complication was a vascular injury with resulting extravasation of contrast medium. In 18/49 procedures (36.7%), coils other than CHMs or vascular plugs were additionally inserted into separate SPCs. CHMs are appropriate for SPC embolization in all age groups, including infants, with a low complication rate. The coils are particularly suitable for the closure of collaterals with a small diameter or tortuous course. They can be used in combination with other embolization devices to achieve comprehensive collateral closure.
体肺侧支血管(SPCs)在先天性心脏病(CHD)中很常见。特别是在单心室解剖结构和Fontan循环中,SPCs既会使术后病程复杂化,又会导致长期临床恶化。SPCs的治疗存在争议。我们研究的目的是(1)回顾性分析使用Concerto™ Helix尼龙纤维微线圈(CHMs)进行SPCs栓塞的患者,以及(2)描述介入技术。在这项单中心回顾性观察队列研究中,我们分析了2016年1月至2023年12月期间所有使用CHMs进行经导管SPCs栓塞的患者的临床和影像学数据。在连续38例患者中(男性占65.8%,中位年龄41个月,范围2 - 490个月),在49次手术中,共向64个SPCs植入了141个CHMs。大多数是源自胸主动脉或其分支的动脉性SPCs(59/64);5/64是静脉 - 静脉性SPCs。所有手术均成功实现了初步封堵。CHMs的直径范围为3至8毫米,最常用的直径为5毫米。平均线圈/SPC比例为2.6(范围1.3 - 5.3)。CHM植入通过4法国鞘进行。解脱和稳定定位都简单且安全。未发生非靶栓塞或线圈移位。1例并发症是血管损伤导致造影剂外渗。在18/49次手术(36.7%)中,除CHMs或血管塞外,还向单独的SPCs额外插入了其他线圈。CHMs适用于包括婴儿在内的所有年龄组的SPCs栓塞,并发症发生率低。这些线圈特别适合于封堵直径小或走行迂曲的侧支血管。它们可与其他栓塞装置联合使用,以实现侧支血管的全面封堵。