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不同手术方法在心脏黏液瘤治疗中的治疗潜力:一项系统评价

The Therapeutic Potential of Different Surgical Approaches in the Management of Cardiac Myxoma: A Systematic Review.

作者信息

Mendyka Dominik, Płonek Tomasz, Jędrasek Tomasz, Korman Adrian, Złotowska Aleksandra, Jędrasek Aleksandra, Skalik Robert, Kustrzycki Wojciech

机构信息

Department of Cardiac Surgery, MEDINET Heart Center Ltd., 51-124 Wrocław, Poland.

Faculty of Medicine, Wroclaw Medical University, 50-367 Wrocław, Poland.

出版信息

J Clin Med. 2024 Dec 28;14(1):121. doi: 10.3390/jcm14010121.

Abstract

Cardiac myxomas are benign tumors of the heart. They occur mostly in the left atrium. The preferred treatment is surgical resection, which can be performed via conventional median sternotomy, minimally invasive, or robotic-assisted approaches. This study aimed to evaluate the outcomes, advantages, and limitations of these surgical methods, with a focus on their safety, efficacy, and impact on patient recovery. This systemic review was conducted according to PRISMA guidelines. The chosen databases were systematically searched using the keywords "cardiac myxoma", "resection", "approach", "minimally invasive", and "robotic surgery". The comparison between the surgical strategies was based on thirteen articles, which met the inclusion criteria. Median sternotomy remains the standard technique, providing excellent surgical access but is associated with longer hospital stays, higher blood loss, and increased risk of complications such as stroke. Minimally invasive approaches demonstrated comparable safety with shorter ICU stays, reduced blood loss, and lower postoperative pain but presented challenges, including limited exposure and longer procedure times. Robotic-assisted surgery showed potential as a safe alternative but was limited by high costs and technical demands. However, the data on minimally invasive and robotic methods are limited due to the rarity of cardiac myxomas. The choice of surgical technique should be individualised by considering the tumour size, location, patient condition, and surgeon expertise. Routine postoperative echocardiographic monitoring is essential to detect residual or recurrent tumours. Further studies are needed to validate the long-term efficacy of minimally invasive and robotic approaches.

摘要

心脏黏液瘤是心脏的良性肿瘤。它们大多发生在左心房。首选治疗方法是手术切除,可通过传统正中胸骨切开术、微创或机器人辅助方法进行。本研究旨在评估这些手术方法的疗效、优势和局限性,重点关注其安全性、有效性以及对患者恢复的影响。本系统评价按照PRISMA指南进行。使用关键词“心脏黏液瘤”“切除”“方法”“微创”和“机器人手术”对选定数据库进行系统检索。手术策略之间的比较基于13篇符合纳入标准的文章。正中胸骨切开术仍然是标准技术,能提供良好的手术入路,但与更长的住院时间、更多的失血以及中风等并发症风险增加相关。微创方法显示出相当的安全性,重症监护病房停留时间更短、失血减少、术后疼痛减轻,但也存在挑战,包括暴露有限和手术时间延长。机器人辅助手术显示出作为一种安全替代方法的潜力,但受到高成本和技术要求的限制。然而,由于心脏黏液瘤罕见,关于微创和机器人方法的数据有限。手术技术的选择应根据肿瘤大小、位置、患者情况和外科医生的专业知识进行个体化。术后常规超声心动图监测对于检测残留或复发性肿瘤至关重要。需要进一步研究来验证微创和机器人方法的长期疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0b2/11722112/693f96292798/jcm-14-00121-g001.jpg

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