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儿童原发性心脏肿瘤的外科治疗。

Surgical treatment of primary cardiac tumors in children.

机构信息

Department of Cardiothoracic Surgery, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, No.136, Zhongshan 2nd Road, Yuzhong District, Chongqing, 400014, China.

出版信息

Gen Thorac Cardiovasc Surg. 2024 Feb;72(2):112-120. doi: 10.1007/s11748-023-01958-z. Epub 2023 Jul 29.

Abstract

OBJECTIVE

Summarizing the treatment experience of primary cardiac tumors in children.

METHODS

The date of 24 children with primary cardiac tumors who underwent surgery in our department from July 2003 to September 2022 was collected and analyzed treatment efficacy.

RESULTS

All patients completed the surgery successfully, including 21 cases of complete tumor resection, 2 cases of partial tumor resection, and 1 case of tumor biopsy. The location: 5 cases in the right atrium, 5 cases in the right ventricle, 6 cases in the left atrium, 6 cases in the left ventricle, 1 case in the left, right ventricle and ventricular septum, and 1 case in the ventricular septum. 23 cases were benign: 11 cases of myxoma, 7 cases of fibroma, 3 cases of rhabdomyoma, 1 case of infantile capillary hemangioma, and 1 case of lipoma. There was 1 case of borderline or malignant tumor. 23 patients were discharged successfully, 1 patient died of cardiac failure on the first day after operation. Follow-up was done from 5 months to 19 years and 2 months, 2 cases were lost to follow-up, and 1 case died of cardiac failure in the second year after operation due to severe mitral regurgitation. There was 1 case of tumor biopsy with space-occupying lesion gradually shrinking during follow-up. The prognosis of another 19 children with complete or partial tumor resection was good. There was no recurrence, enlargement, or reoperation of the tumor during the follow-up period.

CONCLUSIONS

Primary cardiac tumors in children are mostly benign. Surgery is effective, but the timing of surgery depends on the patient's condition.

摘要

目的

总结儿童原发性心脏肿瘤的治疗经验。

方法

收集并分析了 2003 年 7 月至 2022 年 9 月期间在我科接受手术的 24 例原发性心脏肿瘤患儿的治疗效果。

结果

所有患者均顺利完成手术,其中 21 例为完全肿瘤切除,2 例为部分肿瘤切除,1 例为肿瘤活检。肿瘤位置:右心房 5 例,右心室 5 例,左心房 6 例,左心室 6 例,左、右心室及室间隔 1 例,室间隔 1 例。23 例为良性:黏液瘤 11 例,纤维瘤 7 例,横纹肌瘤 3 例,婴幼儿毛细血管瘤 1 例,脂肪瘤 1 例。有 1 例交界性或恶性肿瘤。23 例患者顺利出院,1 例患者术后第 1 天死于心力衰竭。随访时间为 5 个月至 19 年 2 个月,失访 2 例,1 例因严重二尖瓣反流于术后第 2 年死于心力衰竭。1 例肿瘤活检患者在随访过程中占位性病变逐渐缩小。另外 19 例完全或部分肿瘤切除患儿的预后良好。在随访期间,肿瘤无复发、增大或再次手术。

结论

儿童原发性心脏肿瘤多为良性。手术治疗有效,但手术时机取决于患者的病情。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c04/10805930/992a8f4167ef/11748_2023_1958_Fig1_HTML.jpg

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