Ducrotté P, Denis P, Galmiche J P, Hellot M F, Desechalliers J P, Colin R, Pasquis P, Hecketsweiler P
Gastroenterol Clin Biol. 1985 Jan;9(1):10-5.
The aim of our work was to study anorectal motility and tension of the rectal wall in 200 constipated adult patients. Anorectal manometry was normal in 88 patients (group A), showed abnormal amplitude of the anorectal inhibitory reflex in 33 patients (group B) and hypertonia and ultraslow waves in 70 patients (group C). These anomalies were: a) reproducible in the 20 patients studied twice; b) observed in patients with enterocolitis, thus not specific of constipation; c) associated with an increased frequency of fecal evacuation difficulties. Despite normal values of tension of the rectal wall: a) the threshold of conscious perception of distension was increased in 14 p. 100 of patients; b) a paradoxical relationship between the anorectal inhibitory reflex and rectal tension was observed in group B patients. Our results support the concept of outlet obstruction due to anorectal dysfunction and suggest the possibility of neurologic and or ischemic mechanisms in group B patients.
我们研究的目的是对200名成年便秘患者的肛门直肠运动及直肠壁张力进行研究。88例患者（A组）的肛门直肠测压结果正常，33例患者（B组）显示肛门直肠抑制反射幅度异常，70例患者（C组）出现张力亢进及超慢波。这些异常表现为：a）在接受两次检查的20例患者中可重现；b）在患有小肠结肠炎的患者中观察到，因此并非便秘所特有；c）与排便困难频率增加相关。尽管直肠壁张力值正常：a）14%的患者对扩张的自觉感知阈值升高；b）在B组患者中观察到肛门直肠抑制反射与直肠张力之间存在矛盾关系。我们的结果支持因肛门直肠功能障碍导致出口梗阻的概念，并提示B组患者存在神经和/或缺血机制的可能性。
