Moshammer Maximilian, Hecker Andrzej, Watzinger Nikolaus, Pignet Anna-Lisa, Martin Ron, Weigel Gerlinde, Kamolz Lars-Peter, Girsch Werner
Division of Plastic, Aesthetic and Reconstructive Surgery, Department of Surgery, Medical University of Graz, 8036 Graz, Austria.
COREMED-Centre for Regenerative Medicine and Precisions Medicine, Neue Stiftingtalstrasse 2, 8010 Graz, Austria.
J Clin Med. 2024 Dec 30;14(1):157. doi: 10.3390/jcm14010157.
Non-healing soft tissue defects pose challenges to treating physicians. Microsurgical reconstruction is a treatment option for achieving wound closure and limb salvage. These free tissue transfers are often challenging due to associated risk factors. This study aimed to evaluate microsurgical reconstruction using specialized microsurgical techniques for non-healing spontaneous or post-traumatic soft tissue defects in an elderly, high-risk patient cohort with peripheral artery disease. : A retrospective study was conducted on patients with radiologically confirmed peripheral artery disease who underwent free tissue transfers between 2004 and 2010. Patients were included in whom one of two surgical techniques was used, including a "Y" configuration of the arterial pedicle, employed either as an interposition graft or as an arterial patch, or the use of a saphenous vein graft. Patient demographics, comorbidities, flap/limb survival, and surgical techniques were analyzed. : Twenty patients at a mean age of 68 (+/-9.3) years underwent 21 primary flap surgeries. Trauma-derived soft tissue defects were predominant (55%). Latissimus dorsi muscle flaps were most frequently utilized (52.4%). The flap success rate was 90.5% at a 12-month follow-up, with no secondary amputations recorded. The lost flaps were replaced by additional free tissue transfers without further complications. : This study demonstrates the feasibility of free tissue transfers in high-risk patients with complex soft tissue defects and vascular calcifications. Thorough preoperative planning and the application of specialized surgical techniques are crucial for favorable outcomes in challenging clinical scenarios.
难愈性软组织缺损给治疗医生带来了挑战。显微外科重建是实现伤口闭合和肢体挽救的一种治疗选择。由于相关风险因素,这些游离组织移植往往具有挑战性。本研究旨在评估在患有外周动脉疾病的老年高危患者队列中,使用专门的显微外科技术对难愈性自发性或创伤后软组织缺损进行显微外科重建的效果。:对2004年至2010年间接受游离组织移植且经放射学证实患有外周动脉疾病的患者进行了一项回顾性研究。纳入使用以下两种手术技术之一的患者,包括将动脉蒂做成“Y”形配置,用作间置移植物或动脉补片,或使用大隐静脉移植物。分析了患者的人口统计学特征、合并症、皮瓣/肢体存活率及手术技术。:20例平均年龄为68(±9.3)岁的患者接受了21次一期皮瓣手术。创伤性软组织缺损占主导(55%)。背阔肌皮瓣使用最为频繁(52.4%)。在12个月的随访中,皮瓣成功率为90.5%,未记录到二次截肢情况。失活的皮瓣通过额外的游离组织移植进行替换,未出现进一步并发症。:本研究证明了在患有复杂软组织缺损和血管钙化的高危患者中进行游离组织移植的可行性。全面的术前规划和应用专门的手术技术对于在具有挑战性的临床情况下取得良好结果至关重要。