Erkan Merve, Ozcan Seray Gizem Gur
Department of Radiology, Bursa City Hospital, 16110 Bursa, Turkey.
Department of Radiology, Bursa Yuksek Ihtisas Training and Research Hospital, 16310 Bursa, Turkey.
J Clin Med. 2025 Jan 5;14(1):264. doi: 10.3390/jcm14010264.
: This study aimed to evaluate the diagnostic performance of the Kaiser score (KS) on the modified abbreviated breast magnetic resonance imaging (AB-MRI) protocol for characterizing breast lesions by comparing it with full-protocol MRI (FP-MRI), using the histological data as the reference standard. : Breast MRIs detecting histologically verified contrast-enhancing breast lesions were evaluated retrospectively. A modified AB-MRI protocol was created from the standard FP-MRI, which comprised axial fat-suppressed T2-weighted imaging (T2WI), pre-contrast T1-weighted imaging (T1WI), and first, second, and fourth post-contrast phases. Two radiologists reviewed both protocols, recording the KS for each detected lesion. Sensitivity, specificity, and positive and negative predictive values, as well as accuracy, were calculated for each protocol. Receiver operating characteristic (ROC) analysis was performed to determine the diagnostic performance of the modified AB-MRI compared to the FP-MRI. : In total, 154 patients with 158 histopathologically proven lesions (107 malignant, 51 benign) were included. For the diagnostic performance of the KS for modified AB-MRI and FP-MRI, the sensitivity was 96.3% vs. 98.1%, the specificity was 78.4% vs. 74.5%, PPV was 90.4% vs. 89%, NPV was 90.9% vs. 95%, and the diagnostic accuracy was 90.5% vs. 90.5%. The area under the curve (AUC) obtained from the ROC curve analysis was 0.873 and 0.863 for modified AB-MRI and FP-MRI for reader 1, respectively, and 0.859 and 0.878 for modified AB-MRI and FP-MRI for reader 2, respectively, ( < 0.001). : Our modified AB-MRI protocol revealed comparable results in terms of the diagnostic value of the KS in characterizing breast lesions compared to FP-MRI and reduced both scanning and interpretation time.
本研究旨在通过将凯泽评分(KS)与全协议磁共振成像(FP-MRI)进行比较,以组织学数据作为参考标准,评估改良简化乳腺磁共振成像(AB-MRI)协议中KS对乳腺病变特征的诊断性能。对检测到经组织学证实的对比增强乳腺病变的乳腺磁共振成像进行回顾性评估。从标准FP-MRI创建了一种改良的AB-MRI协议,该协议包括轴向脂肪抑制T2加权成像(T2WI)、对比前T1加权成像(T1WI)以及对比后第一、第二和第四期。两名放射科医生审查了这两种协议,记录每个检测到的病变的KS。计算每种协议的敏感性、特异性、阳性和阴性预测值以及准确性。进行受试者操作特征(ROC)分析以确定改良AB-MRI与FP-MRI相比的诊断性能。总共纳入了154例患者,有158个经组织病理学证实的病变(107个恶性,51个良性)。对于改良AB-MRI和FP-MRI的KS诊断性能,敏感性分别为96.3%和98.1%,特异性分别为78.4%和74.5%,阳性预测值分别为90.4%和89%,阴性预测值分别为90.9%和95%,诊断准确性分别为90.5%和90.5%。对于读者1,改良AB-MRI和FP-MRI从ROC曲线分析获得的曲线下面积(AUC)分别为0.873和0.863,对于读者2,改良AB-MRI和FP-MRI的AUC分别为0.859和0.878(<0.001)。我们的改良AB-MRI协议在KS对乳腺病变特征的诊断价值方面与FP-MRI相比显示出可比的结果,并且减少了扫描和解读时间。