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腹腔镜袖状胃切除术治疗Ⅲ级肥胖患者的感染与吻合口漏:一项回顾性研究

infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study.

作者信息

Kazim Albaraa H, Bamehriz Fahad Y, Althwanay Aldanah M, Aldohayan Abdullah, Abdullah Al-Bandari Zamil, AlShehri Bandar, AlTuwayr Rakan Masoud, Razack Habeeb I A, Tamim Hani, Alsohaibani Fahad, Alqahtani Saleh A

机构信息

Bariatric and Upper Gastro-Intestinal Surgery Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

AlNoor Specialist Hospital, Makkah, Saudi Arabia.

出版信息

BMJ Open Gastroenterol. 2024 Dec 20;11(1):e001622. doi: 10.1136/bmjgast-2024-001622.

DOI:10.1136/bmjgast-2024-001622
PMID:39797659
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11664374/
Abstract

OBJECTIVE

Globally, over 50% of the population is affected by , yet research on its prevalence and impact in patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG) is inconclusive. This study aimed to assess the prevalence of infection in individuals with obesity undergoing LSG, evaluate the percentage of postoperative staple-line leaks, and explore the potential link between infection and staple-line leaks.

METHODS

This retrospective analysis assessed adult patients with class III obesity who underwent LSG between 2015 and 2020 at a tertiary care hospital in Riyadh, Saudi Arabia. Patient characteristics with and without postoperative staple-line leaks were compared, exploring the link between infection and these leaks.

RESULTS

Of the 2099 patients (mean age, 34.7±12.2 years; female, 53.5%) included, 35% had infection and 2% experienced post-LSG staple-line leaks. Patients with were older (36.1±11.8 vs 34.0±12.3 years, p<0.0001). Patients with leaks were older, mostly male, and had higher body mass index (p<0.05). However, only 29% of those with leaks were -positive. A non-significant association was found between infection and staple-line leaks (adjusted OR 0.73, 95% CI 0.33 to 1.60, accounting for age, body mass index, and sex).

CONCLUSIONS

Although over one-third of patients with class III obesity undergoing LSG had infection, a non-significant association was observed with post-LSG staple-line leaks, suggesting routine preoperative screening may not be necessary.

摘要

目的

在全球范围内,超过50%的人口受到[某种感染]影响,但关于其在接受腹腔镜袖状胃切除术(LSG)的肥胖患者中的患病率及影响的研究尚无定论。本研究旨在评估接受LSG的肥胖个体中[某种感染]的患病率,评估术后吻合口漏的百分比,并探讨[某种感染]与吻合口漏之间的潜在联系。

方法

这项回顾性分析评估了2015年至2020年期间在沙特阿拉伯利雅得一家三级医疗中心接受LSG的III级肥胖成年患者。比较了有和没有术后吻合口漏的患者特征,探讨[某种感染]与这些漏之间的联系。

结果

纳入的2099例患者(平均年龄34.7±12.2岁;女性占53.5%)中,35%有[某种感染],2%发生了LSG术后吻合口漏。有[某种感染]的患者年龄较大(36.1±11.8岁对34.0±12.3岁,p<0.0001)。发生吻合口漏的患者年龄较大,多为男性,且体重指数较高(p<0.05)。然而,只有29%的漏患者[某种感染]呈阳性。在[某种感染]与吻合口漏之间发现了无显著意义的关联(校正比值比0.73,95%可信区间0.33至1.60,校正了年龄、体重指数和性别)。

结论

尽管超过三分之一接受LSG的III级肥胖患者有[某种感染],但观察到与LSG术后吻合口漏无显著关联,提示常规术前[某种感染]筛查可能没有必要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4759/11664374/bfca8b5c65e1/bmjgast-11-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4759/11664374/7e43a64c9635/bmjgast-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4759/11664374/bfca8b5c65e1/bmjgast-11-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4759/11664374/7e43a64c9635/bmjgast-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4759/11664374/bfca8b5c65e1/bmjgast-11-1-g002.jpg

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Helicobacter pylori infection causes both protective and deleterious effects in human health and disease.幽门螺杆菌感染在人类健康和疾病中既具有保护作用,也具有有害作用。
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