Heydari Mohammad Amin, Hadavi Hadi, Kouhestani Maryam, Iranpour Maryam
School of Medicine, Kerman University of Medical Science, Kerman, Iran.
Department of Surgery, Shahid Bahonar Hospital, Kerman University of Medical Science, Kerman, Iran.
Ann Med Surg (Lond). 2022 Apr 1;76:103548. doi: 10.1016/j.amsu.2022.103548. eCollection 2022 Apr.
Among the bariatric surgery procedures, laparoscopic sleeve gastrectomy (LSG) is one of the most common methods for effective and permanent weight loss among patients with severe obesity. Nonetheless, the LSG can be associated with long-term and short-term complications for the patient. The present study is aimed to investigate the effect of Helicobacter pylori on the complications of LSG, to answer the question of whether eradication of Helicobacter pylori in patients undergoing surgery can be effective in reducing postoperative complications.
In the present analytical-cross sectional study, which has been conducted in Shahid Bahonar Hospital in Kerman during 2018-2020, a total of 100 patients (including 38 males and 62 females) with an average age of 34.8 ± 2.4 years and an average BMI of 41.1 ± 3.1 underwent LSG surgery. After the operation, the gastric mucus specimens were taken from all patients for pathological examination of Helicobacter pylori infection.
According to the results, 28 patients (28%) tested positive for Helicobacter pylori infection (HP positive), and 72 patients (72%) tested negative in this regard (HP negative). The results indicated no significant difference between the HP positive and HP negative patients in terms of demographic characteristics (age, gender, BMI). Overall, 11 patients (11%) exhibited postoperative complications of the LSG including 7 cases (7%) of the SSI, 2 cases (2%) of intraoperative bleeding, and 2 cases (2%) of leakage . Out of the 11 patients with postoperative complications, 6 patients were HP positive including 4 cases of SSI, 1 case of bleeding, and 1 case of leakage.
As indicated by the obtained results, the HP infection has seemingly no impact on the LSG postoperative complications. Nevertheless, it is necessary to conduct further studies on a larger number of patients with a longer follow-up time focusing on the effect of other parameters, such as BMI and underlying diseases.
在减肥手术中，腹腔镜袖状胃切除术（LSG）是重度肥胖患者有效且持久减重的最常用方法之一。尽管如此，LSG可能会给患者带来长期和短期并发症。本研究旨在调查幽门螺杆菌对LSG并发症的影响，以回答手术患者根除幽门螺杆菌是否能有效减少术后并发症这一问题。
在2018年至2020年于克尔曼的沙希德·巴霍纳尔医院进行的这项分析性横断面研究中，共有100例患者（包括38名男性和62名女性）接受了LSG手术，平均年龄为34.8±2.4岁，平均BMI为41.1±3.1。术后，从所有患者中采集胃黏液标本进行幽门螺杆菌感染的病理检查。
根据结果，28例患者（28%）幽门螺杆菌感染检测呈阳性（HP阳性），72例患者（72%）在这方面检测呈阴性（HP阴性）。结果表明，HP阳性和HP阴性患者在人口统计学特征（年龄、性别、BMI）方面无显著差异。总体而言，11例患者（11%）出现了LSG术后并发症，包括7例（7%）手术部位感染、2例（2%）术中出血和2例（2%）渗漏。在11例有术后并发症的患者中，6例为HP阳性，包括4例手术部位感染、1例出血和1例渗漏。
所得结果表明，HP感染似乎对LSG术后并发症没有影响。然而，有必要针对更多患者进行更长时间的随访研究，重点关注其他参数的影响，如BMI和基础疾病。
