α-茄碱对大鼠肠道活性钙转运的影响。
The effect of alpha-solanine on the active calcium transport in rat intestine.
作者信息
Michalska L, Nagel G, Swiniarski E, Zydowo M M
出版信息
Gen Pharmacol. 1985;16(1):69-70. doi: 10.1016/0306-3623(85)90273-3.
PMID:3979798
Abstract
Solanine, an alkaloid isolated from potatoes was found to inhibit active calcium transport in rat duodenum both when added to the everted intestine sacs in vitro and when given to the rats in drinking water for 12 days. The inhibition by solanine of the active calcium transport in the rat intestine was found to be noncompetitive, the inhibitory constant being 25 microM.
摘要
从土豆中分离出的一种生物碱——茄碱，在体外添加到外翻肠囊中以及给大鼠饮用含茄碱的水12天时，均被发现能抑制大鼠十二指肠中的活性钙转运。茄碱对大鼠肠道中活性钙转运的抑制作用被发现是非竞争性的，抑制常数为25微摩尔。
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